Evidence map›Paper›PMID 37046659›Full record

ReviewCancers2023

Pediatric Extracranial Germ Cell Tumors: Review of Clinics and Perspectives in Application of Autologous Stem Cell Transplantation.

Chong-Zhi Lew, Hsi-Che Liu, Jen-Yin Hou, Ting-Huan Huang, Ting-Chi Yeh

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chong-Zhi LewDivision of Pediatric Hematology-Oncology, Department of Pediatrics, Mackay Children's Hospital, Mackay Medical College, Taipei 104, Taiwan.ORCID 0009-0006-0186-2237
Hsi-Che LiuDivision of Pediatric Hematology-Oncology, Department of Pediatrics, Mackay Children's Hospital, Mackay Medical College, Taipei 104, Taiwan.ORCID 0000-0001-9721-167X
Jen-Yin HouDivision of Pediatric Hematology-Oncology, Department of Pediatrics, Mackay Children's Hospital, Mackay Medical College, Taipei 104, Taiwan.ORCID 0000-0002-0716-0838
Ting-Huan HuangDivision of Pediatric Hematology-Oncology, Department of Pediatrics, Hsinchu Mackay Memorial Hospital, Hsinchu 300, Taiwan.ORCID 0000-0002-9336-3147
Ting-Chi YehDivision of Pediatric Hematology-Oncology, Department of Pediatrics, Mackay Children's Hospital, Mackay Medical College, Taipei 104, Taiwan.ORCID 0000-0003-0437-3130
Mackay Medical University · TWMackay Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric extracranial germ cell tumors (GCTs) are rare, accounting for approximately 3.5% of childhood cancers. Since the introduction of platinum-based chemotherapy, the survival rate of patients has improved to more than 80%. However, poor-risk subtypes of pediatric extracranial GCTs do not respond well to chemotherapy, leading to refractory or relapsed (R/R) diseases. For example, long-term survival rates of mediastinal GCTs or choriocarcinoma are less than 50%. According to reports in recent years for adult patients with R/R GCTs, the use of high-dose chemotherapy (HDCT) combined with autologous stem cell transplantation (ASCT) has clinical advantages; however, HDCT combined with ASCT has rarely been reported in pediatric GCTs. The R/R and poor-risk groups of pediatric GCTs could benefit from HDCT and ASCT.

Indexed as

autologous stem cell transplantationextracranialgerm cell tumorhigh-dose chemotherapypediatric

Identifiers

PMID37046659
PMCPMC10093083
OpenAlexW4361216063

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.