Evidence map›Paper›PMID 37047421›Full record

ArticleInternational journal of molecular sciences2023

Cancer Cell-Derived PDGFB Stimulates mTORC1 Activation in Renal Carcinoma.

Asmaa Y Abuhamad, Nurul Nadia Mohamad Zamberi, Sakari Vanharanta, Siti Nur Hasanah Mohd Yusuf, M Aiman Mohtar, Saiful Effendi Syafruddin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  3. FAPNature communications · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Asmaa Y AbuhamadBionanotechnology Research Group, Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.ORCID 0000-0001-5827-1610
Nurul Nadia Mohamad ZamberiUKM Medical Molecular Biology Institute, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, Bandar Tun Razak, Kuala Lumpur 56000, Malaysia.ORCID 0000-0002-6620-1070
Sakari VanharantaDepartment of Physiology, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Siti Nur Hasanah Mohd YusufUKM Medical Molecular Biology Institute, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, Bandar Tun Razak, Kuala Lumpur 56000, Malaysia.
M Aiman MohtarUKM Medical Molecular Biology Institute, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, Bandar Tun Razak, Kuala Lumpur 56000, Malaysia.ORCID 0000-0002-9015-9802
Saiful Effendi SyafruddinUKM Medical Molecular Biology Institute, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, Bandar Tun Razak, Kuala Lumpur 56000, Malaysia.ORCID 0000-0002-9960-4888
University Kebangsaan Malaysia Medical Centre · MYUniversiti Putra Malaysia · MYUniversity of Helsinki · FI

Funding

Akademi Sains Malaysia-Majlis Kanser Negara (MAKNA) Cancer Research Award JJ-2020-001Higher Institute Centre of Excellence Grant (HiCOE) AKU49
6 · The paper itself

Abstract

Clear cell renal cell carcinoma (ccRCC) is a hypervascular tumor that is characterized by bi-allelic inactivation of the

Indexed as

Carcinoma, Renal CellKidney NeoplasmsBecaplerminCell Line, TumorGene Expression Regulation, NeoplasticHumansMechanistic Target of Rapamycin Complex 1Proto-Oncogene Proteins c-sisVon Hippel-Lindau Tumor Suppressor ProteinBecaplerminMechanistic Target of Rapamycin Complex 1Proto-Oncogene Proteins c-sisVon Hippel-Lindau Tumor Suppressor ProteinCRISPR/Cas9KLF6mTOR signalling pathwayPDGFBrenal cancer

Identifiers

PMID37047421
PMCPMC10095210
OpenAlexW4361279121

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.