Evidence map›Paper›PMID 37047783›Full record

ArticleInternational journal of molecular sciences2023

Extracellular Vesicles and Their Zeta Potential as Future Markers Associated with Nutrition and Molecular Biomarkers in Breast Cancer.

Herminia Mendivil-Alvarado, Ana Teresa Limon-Miro, Elizabeth Carvajal-Millan, Jaime Lizardi-Mendoza, Araceli Mercado-Lara, Carlos D Coronado-Alvarado, María L Rascón-Durán, Iván Anduro-Corona, Daniel Talamás-Lara, Antonio Rascón-Careaga and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Article
  5. Review
  6. Does extracellular vesicle specificity truly exist?Cell communication and signaling : CCS · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Herminia Mendivil-AlvaradoDepartment of Nutrition, Research Center for Food and Development, CIAD, A.C., Hermosillo 83304, Mexico.
Ana Teresa Limon-MiroDepartment of Nutrition, Research Center for Food and Development, CIAD, A.C., Hermosillo 83304, Mexico.
Elizabeth Carvajal-MillanDepartment of Nutrition, Research Center for Food and Development, CIAD, A.C., Hermosillo 83304, Mexico.ORCID 0000-0003-4390-7457
Jaime Lizardi-MendozaDepartment of Nutrition, Research Center for Food and Development, CIAD, A.C., Hermosillo 83304, Mexico.ORCID 0000-0003-4636-4371
Araceli Mercado-LaraUndersecretariat of Prevention and Health Promotion, Secretary of Health of the Government of Mexico, Mexico City 11570, Mexico.
Carlos D Coronado-AlvaradoDepartment of Nutrition, Research Center for Food and Development, CIAD, A.C., Hermosillo 83304, Mexico.
María L Rascón-DuránDepartment of Chemical and Biological Sciences, University of Sonora, Hermosillo 83000, Mexico.
Iván Anduro-CoronaDepartment of Nutrition, Research Center for Food and Development, CIAD, A.C., Hermosillo 83304, Mexico.ORCID 0000-0002-2345-8933
Daniel Talamás-LaraDepartment of Infectomics and Molecular Pathogenesis, Center for Research and Advanced Studies, IPN, Mexico City 14330, Mexico.ORCID 0000-0002-0982-2241
Antonio Rascón-CareagaDepartment of Chemical and Biological Sciences, University of Sonora, Hermosillo 83000, Mexico.
Humberto Astiazarán-GarcíaDepartment of Nutrition, Research Center for Food and Development, CIAD, A.C., Hermosillo 83304, Mexico.ORCID 0000-0002-2452-0057
Centro de Investigación en Alimentación y Desarrollo · MXUniversidad de Sonora · MXFederal Government of Mexico · MXInstituto Politécnico Nacional · MXUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A nutritional intervention promotes the loss of body and visceral fat while maintaining muscle mass in breast cancer patients. Extracellular vesicles (EVs) and their characteristics can be potential biomarkers of disease. Here, we explore the changes in the Zeta potential of EVs; the content of miRNA-30, miRNA-145, and miRNA-155; and their association with body composition and biomarkers of metabolic risk in breast cancer patients, before and 6 months after a nutritional intervention. Clinicopathological data (HER2neu, estrogen receptor, and Ki67), anthropometric and body composition data, and plasma samples were available from a previous study. Plasma EVs were isolated and characterized in 16 patients. The expression of miRNA-30, miRNA-145, and miRNA-155 was analyzed. The Zeta potential was associated with HER2neu (β = 2.1;

Indexed as

Breast NeoplasmsExtracellular VesiclesMicroRNAsBiomarkersFemaleHumansKi-67 AntigenNutritional StatusBiomarkersKi-67 AntigenMicroRNAsMIRN145 microRNA, humanMIRN155 microRNA, humanexosomesextracellular communicationmicrovesiclesnutritional status

Identifiers

PMID37047783
PMCPMC10094966
OpenAlexW4362670840

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.