Evidence map›Paper›PMID 37049576›Full record

Trial reportNutrients2023

Effect of an Immune-Boosting, Antioxidant and Anti-Inflammatory Food Supplement in Hospitalized COVID-19 Patients: A Prospective Randomized Pilot Study.

Sandra Reino-Gelardo, Marta Palop-Cervera, Nieves Aparisi-Valero, Ignacio Espinosa-San Miguel, Noelia Lozano-Rodríguez, Gonzalo Llop-Furquet, Laura Sanchis-Artero, Ernesto Cortés-Castell, Mercedes Rizo-Baeza, Xavier Cortés-Rizo

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Chemical Compositions ofInternational journal of molecular sciences · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sandra Reino-GelardoInternal Medicine Department, Hospital of Sagunto, 46520 Sagunto, Spain.
Marta Palop-CerveraInternal Medicine Department, Hospital of Sagunto, 46520 Sagunto, Spain.
Nieves Aparisi-ValeroClinical Analysis and Microbiology Service, Hospital of Sagunto, 46520 Sagunto, Spain.
Ignacio Espinosa-San MiguelInternal Medicine Department, Hospital of Sagunto, 46520 Sagunto, Spain.
Noelia Lozano-RodríguezClinical Analysis and Microbiology Service, Hospital of Sagunto, 46520 Sagunto, Spain.
Gonzalo Llop-FurquetClinical Analysis and Microbiology Service, Hospital of Sagunto, 46520 Sagunto, Spain.
Laura Sanchis-ArteroInternal Medicine Department, Hospital of Sagunto, 46520 Sagunto, Spain.ORCID 0000-0001-7038-6429
Ernesto Cortés-CastellDepartment of Pharmacology, Pediatrics and Organic Chemistry, Miguel Hernández University, 03690 Alicante, Spain.ORCID 0000-0002-6929-9587
Mercedes Rizo-BaezaDepartment of Nursing, University of Alicante, 03690 Alicante, Spain.
Xavier Cortés-RizoInternal Medicine Department, Hospital of Sagunto, 46520 Sagunto, Spain.ORCID 0000-0002-8032-8211
Hospital de Sagunto · ESUniversidad Cardenal Herrera CEU · ESUniversitat de Miguel Hernández d'Elx · ESUniversity of Alicante · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 disease is a serious global health problem. Few treatments have been shown to reduce mortality and accelerate time to recovery. The aim of this study was to evaluate the potential effect of a food supplement (probiotics, prebiotics, vitamin D, zinc and selenium) in patients admitted with COVID-19.

methodsA prospective randomized non-blinded clinical trial was conducted in a sample of 162 hospitalized patients diagnosed with COVID-19 recruited over eight months. All patients received standard treatment, but the intervention group (

resultsROC curve analysis with an area under the curve (AUC) value of 0.840 (

conclusionsIn this trial, the administration of a food supplement (Gasteel Plus

Indexed as

COVID-19Anti-Inflammatory AgentsAntioxidantsDietary SupplementsHumansPilot ProjectsProspective StudiesSARS-CoV-2Treatment OutcomeAnti-Inflammatory AgentsAntioxidantsanti-inflammatoryantioxidantCOVID-19food supplement

Identifiers

PMID37049576
PMCPMC10096722
OpenAlexW4362587062

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.