Evidence map›Paper›PMID 37056573›Full record

ArticleTheranostics2023

Xeno-free cultured mesenchymal stromal cells release extracellular vesicles with a "therapeutic" miRNA cargo ameliorating cartilage inflammation

Maria Elisabetta F Palamà, Simona Coco, Georgina M Shaw, Daniele Reverberi, Maddalena Ghelardoni, Paola Ostano, Giovanna Chiorino, Laura Sercia, Luana Persano, Maria Cristina Gagliani and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  12. From pathogenesis to therapy: extracellular vesicles in osteoarthritis.Frontiers in bioengineering and biotechnology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Maria Elisabetta F PalamàDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
Simona CocoLung Cancer Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Georgina M ShawRegenerative Medicine Institute, National University of Ireland Galway, Galway, Ireland.
Daniele ReverberiU.O. Molecular Pathology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Maddalena GhelardoniDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
Paola OstanoCancer Genomics Lab, Fondazione Edo ed Elvo Tempia, Biella, Italy.
Giovanna ChiorinoCancer Genomics Lab, Fondazione Edo ed Elvo Tempia, Biella, Italy.
Laura SerciaInstitute of Nanoscience (CNR-NANO), Pisa, Italy.
Luana PersanoInstitute of Nanoscience (CNR-NANO), Pisa, Italy.
Maria Cristina GaglianiDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
Katia CorteseDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
Dario PisignanoInstitute of Nanoscience (CNR-NANO), Pisa, Italy.
Josephine Mary MurphyRegenerative Medicine Institute, National University of Ireland Galway, Galway, Ireland.
Chiara GentiliDepartment of Experimental Medicine, University of Genoa, Genoa, Italy.
University of Genoa · ITIstituto Nanoscienze · ITFondazione Edo ed Elvo Tempia · ITOllscoil na Gaillimhe – University of Galway · IEOspedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell Culture TechniquesMesenchymal Stem CellsMicroRNAsOsteoarthritisCartilageChondrocytesDinoprostoneExtracellular VesiclesHumansInterleukin-1alphaIn Vitro TechniquesNF-kappa BSerum Albumin, BovineDinoprostoneIL1A protein, humanInterleukin-1alphaMicroRNAsMIRN145 microRNA, humanMIRN214 microRNA, humanNF-kappa BSerum Albumin, Bovineextracellular vesiclesmesenchymal stromal cellsmicroRNAosteoarthritisxeno free medium

Identifiers

PMID37056573
PMCPMC10086204
OpenAlexW4324010181

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.