Evidence map›Paper›PMID 37065092›Full record

ArticleBrain communications2023

Homeostatic normalization of alpha brain rhythms within the default-mode network and reduced symptoms in post-traumatic stress disorder following a randomized controlled trial of electroencephalogram neurofeedback.

Andrew A Nicholson, Maria Densmore, Paul A Frewen, Richard W J Neufeld, Jean Théberge, Rakesh Jetly, Ruth A Lanius, Tomas Ros

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  15. Article
  16. tDCS and neurofeedback in ADHD treatment.Frontiers in systems neuroscience · 2025
    Review
  17. Article
  18. Reflecting onJournal of military, veteran and family health · 2024
    Article
  19. Journal of military, veteran and family health · 2024
    Article
  20. Towards predicting PTSD symptom severity using portable EEG-derived biomarkers.medRxiv : the preprint server for health sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Andrew A NicholsonSchool of Psychology, University of Ottawa, Ottawa, Canada.ORCID https://orcid.org/0000-0002-9483-5628
Maria DensmoreDepartment of Neuroscience, Western University, London, Canada.
Paul A FrewenDepartment of Neuroscience, Western University, London, Canada.ORCID https://orcid.org/0000-0003-3578-4776
Richard W J NeufeldDepartment of Neuroscience, Western University, London, Canada.
Jean ThébergeDepartment of Psychiatry, Western University, London, Canada.ORCID https://orcid.org/0000-0001-7578-4469
Rakesh JetlyDefence Research and Development Canada, Toronto, Canada.
Ruth A LaniusDepartment of Neuroscience, Western University, London, Canada.
Tomas RosDepartments of Neuroscience and Psychiatry, University of Geneva; Campus Biotech, Geneva, Switzerland.ORCID https://orcid.org/0000-0001-6952-0459
Western University · CADefence Research and Development Canada · CAUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collective research has identified a key electroencephalogram signature in patients with post-traumatic stress disorder, consisting of abnormally reduced alpha (8-12 Hz) rhythms. We conducted a 20-session, double-blind, randomized controlled trial of alpha desynchronizing neurofeedback in patients with post-traumatic stress disorder over 20 weeks. Our objective was to provide mechanistic evidence underlying potential clinical improvements by examining changes in aberrant post-traumatic stress disorder brain rhythms (namely, alpha oscillations) as a function of neurofeedback treatment. We randomly assigned participants with a primary diagnosis of post-traumatic stress disorder (

Indexed as

alpha reboundEEGneurofeedbackpost-traumatic stress disorder (PTSD)

Identifiers

PMID37065092
PMCPMC10090479
OpenAlexW4327554757

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.