Evidence map›Paper›PMID 37066159›Full record

ArticlebioRxiv : the preprint server for biology2023

Differential Regulation of Retinoic Acid Metabolism in Fanconi Anemia.

Justin L Blaize, Bahaa M Noori, Kelsey P Hunter, Kathryn A Henrikson, Janet A Atoyan, Alan A Ardito, Frank X Donovan, Settara C Chandrasekharappa, Detlev Schindler, Niall G Howlett

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Justin L Blaize
Bahaa M Noori
Kelsey P Hunter
Kathryn A Henrikson
Janet A Atoyan
Alan A Ardito
Frank X Donovan
Settara C Chandrasekharappa
Detlev Schindler
University of Rhode Island · USNational Institutes of Health · USBrown University · USUniversity of Würzburg · DE

Funding

MARC U*STAR Training Program at the University of Rhode Island - Administrative SupplementT34GM131948 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI HOWLETT, NIALL GEORGE · 2019 to 2023
$1.3M
Chromatin State Alterations in Fanconi Anemia Hematologic Disease and Bone Marrow FailureR01HL149907 · NHLBI · UNIVERSITY OF RHODE ISLAND · PI HOWLETT, NIALL GEORGE · 2020 to 2023
$1.2M
NHLBI NIH HHS R01 HL149907NIGMS NIH HHS T34 GM131948
6 · The paper itself

Abstract

Fanconi anemia (FA) is a rare genetic disease characterized by heterogeneous congenital abnormalities and increased risk for bone marrow failure and cancer. FA is caused by mutation of any one of 23 genes, the protein products of which function primarily in the maintenance of genome stability. An important role for the FA proteins in the repair of DNA interstrand crosslinks (ICLs) has been established

Identifiers

PMID37066159
PMCPMC10104110
OpenAlexW4362661760

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.