Evidence map›Paper›PMID 37066164›Full record

ArticlebioRxiv : the preprint server for biology2023

Astrocyte-Secreted Neurocan Controls Inhibitory Synapse Formation and Function.

Dolores Irala, Shiyi Wang, Kristina Sakers, Leykashree Nagendren, Francesco Paolo Ulloa-Severino, Dhanesh Sivadasan Bindu, Cagla Eroglu

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 16 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Leykashree Nagendren
Francesco Paolo Ulloa-SeverinoORCID 0000-0003-3725-9713
Dhanesh Sivadasan BinduORCID 0000-0002-1545-1547
Duke University · USHoward Hughes Medical Institute · US

Funding

Novel Genetically Encoded Indicators for Interrogating Neuron-Astrocyte Communication Across TimescalesU19NS123719 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI TIAN, LIN · 2021 to 2025
$10.7M
New Proteomic and Genome Engineering Approaches to Decipher Astrocyte Function at SynapsesR01DA047258 · NIDA · DUKE UNIVERSITY · PI EROGLU, CAGLA, SODERLING, SCOTT H · 2018 to 2020
$2.1M
Heat Shock Factors and Protein Misfolding DiseaseRF1AG059409 · NIA · DUKE UNIVERSITY · PI EROGLU, CAGLA · 2018 to 2018
$1.9M
Control of Astrocyte Development and Astrocyte-Synapse InteractionsR01NS102237 · NINDS · DUKE UNIVERSITY · PI EROGLU, CAGLA · 2018 to 2022
$1.9M
NIA NIH HHS RF1 AG059409NIDA NIH HHS R01 DA047258NINDS NIH HHS R01 NS102237NINDS NIH HHS U19 NS123719
6 · The paper itself

Abstract

Astrocytes strongly promote the formation and maturation of synapses by secreted proteins. To date, several astrocyte-secreted synaptogenic proteins controlling different stages of excitatory synapse development have been identified. However, the identities of astrocytic signals that induce inhibitory synapse formation remain elusive. Here, through a combination of

Identifiers

PMID37066164
PMCPMC10104008
OpenAlexW4362576374

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.