Evidence mapPaperPMID 37067668Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2023

Gaps Remain for Achieving HbA1c Targets for People with Type 1 or Type 2 Diabetes Using Insulin: Results from NHANES 2009-2020.

Emily R Hankosky, David Schapiro, Karli B Gunn, Elizabeth B Lubelczyk, Jessica Mitroi, David R Nelson

Open access · goldAbstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  14. The role of advanced technologies in improving diabetes outcomes.The American journal of managed care · 2025
    Review
  15. Article
  16. Review
  17. Automating Insulin Dosing and Delivery: The Latest in Algorithms, Calculators, and Devices.Diabetes spectrum : a publication of the American Diabetes Association · 2025
    Article
  18. Assessing the iLet Bionic Pancreas Deployed in Primary Care and via Telehealth: A Randomized Clinical Trial.Clinical diabetes : a publication of the American Diabetes Association · 2025
    Article
  19. Connected Insulin Pens and Pen Caps: Expanding Diabetes Technology Access and Adoption.Diabetes spectrum : a publication of the American Diabetes Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emily R HankoskyValue, Evidence and Outcomes (VEO)-Diabetes, Eli Lilly and Company, Indianapolis, IN, USA. emily.hankosky@lilly.com.
David SchapiroValue, Evidence and Outcomes (VEO)-Diabetes, Eli Lilly and Company, Indianapolis, IN, USA.
Karli B GunnValue, Evidence and Outcomes (VEO)-Diabetes, Eli Lilly and Company, Indianapolis, IN, USA.
Elizabeth B LubelczykValue, Evidence and Outcomes (VEO)-Diabetes, Eli Lilly and Company, Indianapolis, IN, USA.
Jessica MitroiValue, Evidence and Outcomes (VEO)-Diabetes, Eli Lilly and Company, Indianapolis, IN, USA.
David R NelsonValue, Evidence and Outcomes (VEO)-Diabetes, Eli Lilly and Company, Indianapolis, IN, USA.
Eli Lilly (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGlycated hemoglobin A1c (HbA1c) is an important measure to assess glycemic control and predict diabetes complications. However, there is limited information on trends in HbA1c among people with diabetes (PwDs) who use insulin. The aim of this study was to describe trends in HbA1c among PwDs who use insulin by diabetes type and insulin regimen.

methodsA retrospective analysis was conducted using data from the National Health and Nutrition Examination Survey (NHANES, 2009-2020). PwDs were classified into three cohorts: type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus using mealtime insulin (T2DM-MTI), and type 2 diabetes mellitus (T2DM) using basal-only insulin (T2DM basal-only). Trends in HbA1c over time were assessed using regression analysis after adjusting for age, gender, and race/ethnicity.

resultsMean HbA1c values aggregated over 2009-2020 were 8.0% (T1DM), 8.6% (T2DM-MTI), and 8.6% (T2DM basal-only). The American Diabetes Association-recommended target of HbA1c of < 7% was achieved by 25.2% of people in the T1DM and T2DM-MTI groups each and by 12.3% of people in the T2DM basal-only group. Over time, an upward trend was observed in the percentage of people achieving HbA1c < 7% in the T2DM basal-only group. The percentage of PwDs achieving individualized HbA1c targets was 27.0%, 12.4%, and 16.1% for the T1DM, T2DM-MTI, and T2DM basal-only groups, respectively.

conclusionsOur study using NHANES data suggests that approximately 25% of PwDs achieve glycemic targets. This study highlights the need for improved therapies to better manage glycemic targets in PwDs.

Indexed as

Basal insulinGlycemic targetsHbA1cMealtime insulinType 1 diabetes mellitusType 2 diabetes mellitus

Identifiers

PMID37067668
PMCPMC10108820
OpenAlexW4366083274

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.