Evidence map›Paper›PMID 37068913›Full record

ArticleRNA (New York, N.Y.)2023

Anionic G•U pairs in bacterial ribosomal rRNAs.

Eric Westhof, Zoe L Watson, Craig L Zirbel, Jamie H D Cate

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Eric WesthofArchitecture et Réactivité de l'ARN, Université de Strasbourg, Institut de biologie moléculaire et cellulaire du CNRS, F-67084 Strasbourg, France e.westhof@ibmc-cnrs.unistra.fr.ORCID 0000-0002-6172-5422
Zoe L WatsonDepartment of Chemistry, University of California, Berkeley, California 94720, USA.ORCID 0000-0002-4877-7914
Craig L ZirbelDepartment of Mathematics and Statistics, Bowling Green State University, Bowling Green, Ohio 43403, USA.ORCID 0000-0002-3281-918X
Jamie H D CateDepartment of Chemistry, University of California, Berkeley, California 94720, USA.ORCID 0000-0001-5965-7902
Bowling Green State University · USCentre National de la Recherche Scientifique · FRLawrence Berkeley National Laboratory · USQB3 · US

Funding

RNA 3D Motif Search, Atlas, and Prediction from SequenceR01GM085328 · NIGMS · BOWLING GREEN STATE UNIVERSITY · PI ZIRBEL, CRAIG L · 2010 to 2023
$4.0M
NIGMS NIH HHS R01 GM085328
6 · The paper itself

Abstract

Wobble GU pairs (or G•U) occur frequently within double-stranded RNA helices interspersed between standard G=C and A-U Watson-Crick pairs. Another type of G•U pair interacting via their Watson-Crick edges has been observed in the A site of ribosome structures between a modified U34 in the tRNA anticodon triplet and G + 3 in the mRNA. In such pairs, the electronic structure of the U is changed with a negative charge on N3(U), resulting in two H-bonds between N1(G)…O4(U) and N2(G)…N3(U). Here, we report that such pairs occur in other highly conserved positions in ribosomal RNAs of bacteria in the absence of U modification. An anionic

Indexed as

RibosomesRNA, RibosomalAnticodonBacteriaCodonNucleic Acid ConformationAnticodonCodonRNA, RibosomalanionicanticodoncodonG•U pairmRNArRNAtRNA

Identifiers

PMID37068913
PMCPMC10275268
OpenAlexW4366085824

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.