Evidence map›Paper›PMID 37071551›Full record

SynthesisInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2026

The safety profile of single antiplatelet therapy with flow diverters: Systematic review and meta-analysis.

Yigit Can Senol, Atakan Orscelik, Sherief Ghozy, Hassan Kobeissi, Santhosh Arul, Cem Bilgin, Ramanathan Kadirvel, David F Kallmes

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. First clinical experience with the Derivo 2heal embolization device for the treatment of intracranial aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yigit Can SenolDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-6669-6616
Atakan OrscelikDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-6481-3076
Sherief GhozyDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-5629-3023
Hassan KobeissiDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-7446-624X
Santhosh ArulDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Cem BilginDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-6243-9495
Ramanathan KadirvelDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-6786-9953
David F KallmesDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-8495-0040
Mayo Clinic in Arizona · USMayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundDual antiplatelet therapy (DAPT) is frequently used in treating cerebral aneurysms with flow diverters (FDs), whereas single antiplatelet therapy (SAPT) is used mostly with coated FDs and in ruptured aneurysms. We conducted a systematic review and meta-analysis to explore the safety profile of SAPT in FDs.MethodsPubMed, Web of Science, OVID Embase, OVID Medline, and Scopus were searched to 1st November 2022. Outcomes of interest included ischemic and hemorrhagic complications, conversion to DAPTs, and in-stent stenosis rates under long-term SAPT. SAPT is divided into aspirin (ASA) vs. non-ASA group (ticagrelor or prasugrel). Subgroup analysis was performed for ruptured vs. non-ruptured aneurysms and coated vs. non-coated FDs. All data were analyzed using R software version 4.2.2.ResultsTwelve studies with 240 total patients (43 patients in the ASA group and 197 patients in the non-ASA group) were included in our meta-analysis. The pooled ischemic occlusion rate was 9.8% (95% CI = 4.87-18.95:

Indexed as

Endovascular ProceduresIntracranial AneurysmPlatelet Aggregation InhibitorsStentsAneurysm, RupturedAspirinHumansAspirinPlatelet Aggregation Inhibitorsanti-plateletaspirinFlow diverterprasugrelticagrelor

Identifiers

PMID37071551
PMCPMC13305368
OpenAlexW4366242748

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.