Evidence map›Paper›PMID 37073295›Full record

ReviewMarine life science & technology2021

Hepatic cecum: a key integrator of immunity in amphioxus.

Baozhen Qu, Shicui Zhang, Zengyu Ma, Zhan Gao

Open access · greenAbstract readReview
In one paragraph

Review in Marine life science & technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Baozhen QuDepartment of Marine Biology, Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao, 266003 China.
Shicui ZhangDepartment of Marine Biology, Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao, 266003 China.
Zengyu MaDepartment of Marine Biology, Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao, 266003 China.
Zhan GaoDepartment of Marine Biology, Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao, 266003 China.
Ocean University of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vertebrate liver is regarded as an organ essential to the regulation of immunity and inflammation as well as being central to the metabolism of nutrients. Here, we discuss the functions that the hepatic cecum of amphioxus plays in the regulation of immunity and inflammation, and the molecular basis of this. It is apparent that the hepatic cecum performs important roles in the immunity of amphioxus including immune surveillance, clearance of pathogens and acute phase response. Therefore, the hepatic cecum, like the vertebrate liver, is an organ functioning as a key integrator of immunity in amphioxus.

Indexed as

Acute phase responseAmphioxusHepatic cecumImmunityInflammation

Identifiers

PMID37073295
PMCPMC10077268
OpenAlexW3119251984

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.