Evidence map›Paper›PMID 37076902›Full record

ReviewChinese medicine2023

Machine learning in TCM with natural products and molecules: current status and future perspectives.

Suya Ma, Jinlei Liu, Wenhua Li, Yongmei Liu, Xiaoshan Hui, Peirong Qu, Zhilin Jiang, Jun Li, Jie Wang

Abstract readReview
In one paragraph

Review in Chinese medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Suya Ma *Guang'anmen Hospital, China Academy of Chinese Medicine Sciences, Beijing, 100053, China.
Jinlei Liu *Guang'anmen Hospital, China Academy of Chinese Medicine Sciences, Beijing, 100053, China.
Wenhua Li *Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Yongmei LiuGuang'anmen Hospital, China Academy of Chinese Medicine Sciences, Beijing, 100053, China.
Xiaoshan HuiGuang'anmen Hospital, China Academy of Chinese Medicine Sciences, Beijing, 100053, China.
Peirong QuGuang'anmen Hospital, China Academy of Chinese Medicine Sciences, Beijing, 100053, China.
Zhilin JiangGuang'anmen Hospital, China Academy of Chinese Medicine Sciences, Beijing, 100053, China.
Jun LiGuang'anmen Hospital, China Academy of Chinese Medicine Sciences, Beijing, 100053, China. gamyylj@163.com.
Jie WangGuang'anmen Hospital, China Academy of Chinese Medicine Sciences, Beijing, 100053, China. wangjie0103@126.com.ORCID http://orcid.org/0000-0001-7870-0646

Funding

Chief Scientist Office 0201000401
6 · The paper itself

Abstract

Traditional Chinese medicine (TCM) has been practiced for thousands of years with clinical efficacy. Natural products and their effective agents such as artemisinin and paclitaxel have saved millions of lives worldwide. Artificial intelligence is being increasingly deployed in TCM. By summarizing the principles and processes of deep learning and traditional machine learning algorithms, analyzing the application of machine learning in TCM, reviewing the results of previous studies, this study proposed a promising future perspective based on the combination of machine learning, TCM theory, chemical compositions of natural products, and computational simulations based on molecules and chemical compositions. In the first place, machine learning will be utilized in the effective chemical components of natural products to target the pathological molecules of the disease which could achieve the purpose of screening the natural products on the basis of the pathological mechanisms they target. In this approach, computational simulations will be used for processing the data for effective chemical components, generating datasets for analyzing features. In the next step, machine learning will be used to analyze the datasets on the basis of TCM theories such as the superposition of syndrome elements. Finally, interdisciplinary natural product-syndrome research will be established by unifying the results of the two steps outlined above, potentially realizing an intelligent artificial intelligence diagnosis and treatment model based on the effective chemical components of natural products under the guidance of TCM theory. This perspective outlines an innovative application of machine learning in the clinical practice of TCM based on the investigation of chemical molecules under the guidance of TCM theory.

Indexed as

Chemical componentsDeep learningMachine learningMultidisciplinary intersectionNatural productsTraditional Chinese medicine

Identifiers

PMID37076902
PMCPMC10116715

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.