Evidence map›Paper›PMID 37078149›Full record

ArticleJournal of the American Geriatrics Society2023

Adoption of sodium-glucose cotransporter-2 inhibitors among prescribers caring for nursing home residents.

Kaleen N Hayes, Sarah D Berry, Medha N Munshi, Andrew R Zullo

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Kaleen N HayesDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0002-1122-0071
Sarah D BerryHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts, USA.
Medha N MunshiHarvard Medical School, Boston, Massachusetts, USA.
Andrew R ZulloDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0003-1673-4570
Brown University · USHarvard University · USJoslin Diabetes Center · USUniversity of Toronto · CA

Funding

Clinically Significant Drug Interactions among Nursing Home Residents with ADRDR01AG077620 · NIA · BROWN UNIVERSITY · PI Andrew Reis Zullo · 2022 to 2026
$3.5M
Safe Cardiometabolic Drug Prescribing to Prevent Injury in Nursing Home ResidentsRF1AG061221 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI BERRY, SARAH DYER · 2019 to 2019
$2.8M
Benefits and Harms of Long-term Osteoporosis Pharmacotherapy: Impact of Treatment Length, Type, Switching, and HolidaysR01AG078759 · NIA · BROWN UNIVERSITY · PI CADARETTE, SUZANNE, HAYES, KALEEN NICOLE · 2022 to 2025
$2.5M
Medications and the Risk of Motor Vehicle Crashes in Older AdultsR01AG065722 · NIA · BROWN UNIVERSITY · PI ZULLO, ANDREW REIS · 2020 to 2023
$2.1M
Mentoring Patient-Oriented Research to Prevent Injury in Older AdultsK24AG070106 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI Sarah Dyer Berry · 2021 to 2026
$735k
Opioid use in post-acute hip fracture care: prescribing patterns, effectiveness, and safetyR21AG061632 · NIA · BROWN UNIVERSITY · PI BEAUDOIN, FRANCESCA, ZULLO, ANDREW REIS · 2019 to 2020
$462k
NIA NIH HHS K24 AG070106NIA NIH HHS R01 AG065722NIA NIH HHS R01 AG077620NIA NIH HHS R01 AG078759NIA NIH HHS R21 AG061632NIA NIH HHS RF1 AG061221
6 · The paper itself

Abstract

backgroundSodium-glucose cotransporter-2 inhibitor (SGLT2I) use has increased among community-dwelling populations, but little is known about how clinicians have prescribed them for US nursing home (NH) residents. We described the adoption of SGLT2Is by prescribers caring for long-stay NH residents by clinician specialty and over time, compared with sulfonylureas, an older diabetes medication class.

methodsWe conducted a retrospective cohort study of prescribers of SGLT2Is and sulfonylureas for all long-stay US NH residents aged 65 years or older (2017-2019). Using 100% of Medicare Part D claims linked to prescriber characteristics data, we identified all dispensings of SGLT2Is and sulfonylureas for long-stay NH residents and their associated prescribers. We described the distribution of prescriber specialties for each drug class over time as well as the number of NH residents prescribed SGLT2s versus sulfonylureas. We estimated the proportions of prescribers who prescribed both drug classes versus only sulfonylureas or only SGLT2Is.

resultsWe identified 36,427 unique prescribers (SGLT2I: N = 5811; sulfonylureas: N = 35,443) for 117,667 NH residents between 2017 and 2019. For both classes, family medicine and internal medicine physicians accounted for most prescriptions (75%-81%). Most clinicians (87%) prescribed only sulfonylureas, 2% prescribed SGLT2Is only, and 11% prescribed both. Geriatricians were least likely to prescribe only SGLT2Is. We observed an increase in the number of residents with SGLT2I use from n = 2344 in 2017 to n = 5748 in 2019.

conclusionsAmong NH residents, most clinicians have not incorporated SGLT2Is into their prescribing for diabetes, but the extent of use is increasing. Family medicine and internal medicine physicians prescribed the majority of diabetes medications for NH residents, and geriatricians were the least likely to prescribe only SGLT2Is. Future research should explore provider concerns regarding SGLT2I prescribing, particularly adverse events.

Indexed as

Diabetes Mellitus, Type 2Medicare Part DSodium-Glucose Transporter 2 InhibitorsAgedGlucoseHumansHypoglycemic AgentsNursing HomesRetrospective StudiesSodiumSulfonylurea CompoundsUnited StatesGlucoseHypoglycemic AgentsSodiumSodium-Glucose Transporter 2 InhibitorsSulfonylurea Compoundsfrail elderlyhypoglycemic agentsnursing homessodium-glucose transporter 2 inhibitorssulfonylurea compounds

Identifiers

PMID37078149
PMCPMC10528819
OpenAlexW4366463088

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.