Evidence map›Paper›PMID 37079534›Full record

ArticlePloS one2023

The impact of the COVID-19 lockdown on birthweight among singleton term birth in Denmark.

Victoria E de Knegt, Paula L Hedley, Gitte Hedermann, Casper Wilstrup, Marie Bækvad-Hansen, Ida N Thagaard, Henrik Hjalgrim, Jørgen Kanters, Mads Melbye, David M Hougaard and 5 more

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Victoria E de KnegtDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Paula L HedleyDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.ORCID 0000-0001-5801-960X
Gitte HedermannDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Casper WilstrupDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Marie Bækvad-HansenDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Ida N ThagaardDepartment of Obstetrics and Gynaecology, Copenhagen University Hospital Slagelse, Slagelse, Denmark.
Henrik HjalgrimDepartment of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Jørgen KantersDepartment of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Mads MelbyeDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
David M HougaardDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Anders HviidDepartment of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Lone KrebsDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-5433-4776
Morten BreindahlDepartment of Neonatology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Ulrik Lausten-ThomsenDepartment of Neonatology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0003-1136-4347
Michael ChristiansenDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.ORCID 0000-0003-4713-755X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Denmark, a nationwide COVID-19 lockdown was implemented on March 12, 2020 and eased on April 14, 2020. The COVID-19 lockdown featured reduced prevalence of extremely preterm or extremely low birthweight births. This study aims to explore the impact of this COVID-19 lockdown on term birthweights in Denmark. We conducted a nationwide register-based cohort study on 27,870 live singleton infants, born at term (weeks 37-41), between March 12 and April 14, 2015-2020, using data from the Danish Neonatal Screening Biobank. Primary outcomes, corrected for confounders, were birthweight, small-for-gestational-age (SGA), and large-for-gestational-age (LGA), comparing the COVID-19 lockdown to the previous five years. Data were analysed using linear regression to assess associations with birthweight. Multinomial logistic regression was used to assess associations with relative-size-for-gestational-age (xGA) categories. Adjusted mean birthweight was significantly increased by 16.9 g (95% CI = 4.1-31.3) during the lockdown period. A dip in mean birthweight was found in gestational weeks 37 and 38 balanced by an increase in weeks 40 and 41. The 2020 lockdown period was associated with an increased LGA prevalence (aOR 1.13, 95% CI = 1.05-1.21). No significant changes in proportions of xGA groups were found between 2015 and 2019. The nationwide COVID-19 lockdown resulted in a small but significant increase in birthweight and proportion of LGA infants, driven by an increase in birthweight in gestational weeks 40 and 41.

Indexed as

COVID-19Premature BirthBirth WeightCohort StudiesCommunicable Disease ControlDenmarkFemaleHumansInfant, NewbornPregnancyTerm Birth

Identifiers

PMID37079534
PMCPMC10118089

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.