Evidence map›Paper›PMID 37079580›Full record

ArticlePloS one2023

Omega-3 supplements in the prevention and treatment of youth depression and anxiety symptoms: A scoping review.

Natalie M Reily, Samantha Tang, Ashlee Negrone, Daniel Z Q Gan, Veronica Sheanoda, Helen Christensen

Open access · goldAbstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Observational
  6. Article
  7. Omega-3 Polyunsaturated Fatty Acids in Depression.International journal of molecular sciences · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Natalie M ReilyBlack Dog Institute, University of New South Wales Sydney, Sydney, NSW, Australia.ORCID 0000-0001-7152-0992
Samantha TangBlack Dog Institute, University of New South Wales Sydney, Sydney, NSW, Australia.
Ashlee NegroneBlack Dog Institute, University of New South Wales Sydney, Sydney, NSW, Australia.
Daniel Z Q GanBlack Dog Institute, University of New South Wales Sydney, Sydney, NSW, Australia.
Veronica SheanodaBlack Dog Institute, University of New South Wales Sydney, Sydney, NSW, Australia.
Helen ChristensenBlack Dog Institute, University of New South Wales Sydney, Sydney, NSW, Australia.
Black Dog Institute · AU

Funding

Wellcome Trust
6 · The paper itself

Abstract

introductionOmega-3 supplements may be efficacious in reducing symptoms of depression and anxiety in adults, particularly as an adjunct to antidepressant medication. However, research in young people is limited. Thus, this scoping review aimed to summarise existing evidence on the efficacy of omega-3 supplementation in treating depression and anxiety symptoms in young people aged 14-24. A secondary aim was to determine whether grey literature intended for the general public accurately reflects the evidence.

methodFour databases (Cochrane CENTRAL, EmBASE, PsycINFO, PubMed) were searched from inception to 4th August 2021. Eligible peer-reviewed studies were empirical studies which examined the efficacy of omega-3 supplements in preventing/treating anxiety and/or depression symptoms in young people aged 14-24. Risk of bias was assessed for randomised studies using the Cochrane Risk of Bias Tool. Selected grey literature databases were also searched, with eligible sources assessed for quality. A stakeholder group including young people with lived experience of anxiety/depression, parents/carers and mental health professionals informed the research questions and data interpretation. Findings were summarised using narrative synthesis.

results17 empirical studies (N = 1240 participants) meeting inclusion criteria were identified. Studies varied in treatment and participant characteristics. In general, the data did not support the view that omega-3 supplements were efficacious in improving symptoms of anxiety or depression in young people aged 14-24. In contrast, most grey literature sources recommended the use of omega-3 supplements in young people. DISCUSSION: Evidence for efficacy of omega-3 supplementation in reducing symptoms of depression and anxiety in young people was inconclusive. More research is needed to identify potential mechanisms and moderators of the effect of omega-3 supplements on depression and anxiety symptoms in young people.

Indexed as

AnxietyDepressionAdolescentAdultAntidepressive AgentsAnxiety DisordersCaregiversHumansAntidepressive Agents

Identifiers

PMID37079580
PMCPMC10118139
OpenAlexW4366464214

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.