Evidence map›Paper›PMID 37080957›Full record

ArticleCell discovery2023

A tissue specific-infection mouse model of SARS-CoV-2.

Bo Yang, Chao Liu, Xiaohui Ju, Bingbing Wu, Zhuangfei Wang, Fucheng Dong, Yanying Yu, Xiaohui Hou, Min Fang, Fei Gao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cell discovery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Generation of a humanized mAce2 and a conditional hACE2 mouse models permissive to SARS-COV-2 infection.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Bo Yang *Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, Guangdong, China.
Chao Liu *Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Xiaohui Ju *Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China.
Bingbing WuState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Zhuangfei WangGuangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Fucheng DongState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Yanying YuCenter for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China.
Xiaohui HouZunyi Medical University, Zunyi, Guizhou, China.
Min FangCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-5278-1430
Fei GaoState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-4029-6411
Xuejiang GuoState Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
Yaoting GuiGuangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, Guangdong, China. guiyaoting2007@aliyun.com.ORCID http://orcid.org/0000-0002-5299-8330
Qiang DingCenter for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China. qding@tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-6226-869X
Wei LiGuangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China. leways@gwcmc.org.
Chinese Academy of Sciences · CNTsinghua University · CNPeking University Shenzhen Hospital · CNZunyi Medical University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal models play crucial roles in the rapid development of vaccines/drugs for the prevention and therapy of COVID-19, but current models have some deficits when studying the pathogenesis of SARS-CoV-2 on some special tissues or organs. Here, we generated a human ACE2 and SARS-CoV-2 N

Identifiers

PMID37080957
PMCPMC10117269
OpenAlexW4366549785

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.