Evidence map›Paper›PMID 37082486›Full record

ReviewCureus2023

A Methodological Review of Drug-Related Toxicological Studies in Saudi Arabia.

Hassan Alwafi, Rayan Khayat, Alaa Banjabi, Emad Salawati, Basil J Alotaibi, Rami Nassir, Abdulelah Aldhahir, Rakan Ekram, Saeed M Alghamdi, Abdallah Y Naser

Abstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Essence of toxicology research to Saudi Arabia Vision 2030 and beyond: Current state and future perspectives.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Article
  3. Substance misuse disorder in Saudi Arabia: A comprehensive examination of current demographic patterns, trends, and intervention requirements.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hassan AlwafiPharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Mecca, SAU.
Rayan KhayatToxicology Center, Ministry of Health, Medina, SAU.
Alaa BanjabiMedicine, Ministry of Health, Jeddah, SAU.
Emad SalawatiFamily Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.
Basil J AlotaibiResearch, Independent Researcher, Riyadh, SAU.
Rami NassirPathology, Umm Al-Qura University, Mecca, SAU.
Abdulelah AldhahirRespiratory Therapy, Faculty of Applied Medical Sciences, Jazan, SAU.
Rakan EkramSchool of Public Health and Health Informatics, Umm Al-Qura University, Mecca, SAU.
Saeed M AlghamdiClinical Technology and Respiratory Care, Faculty of Applied Medical Sciences, Umm Al-Qura University, Mecca, SAU.
Abdallah Y NaserApplied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacoepidemiology, Isra University, Amman, JOR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to conduct a methodological review of drug-related toxicological studies in Saudi Arabia. A systematic review and a methodological analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Medline and Embase were searched for all types of studies reporting toxicological studies in the English language published until January 10, 2022. The search was conducted using both keywords and Medical Subject Headings (MeSH) terms. The methodological analysis of included studies was assessed using the Newcastle-Ottawa Scale. A total of 3,750 studies were extracted and screened. Of these, 30 observational studies (seven cohort studies and 23 cross-sectional studies) met the inclusion criteria. The methodological scores ranged from five to seven out of 10 possible points. Twelve studies had high quality, and 18 studies had moderate quality. Eight studies focused on adverse drug reactions, eight explored poisoning, four explored drug-related hospitalizations, nine explored drug-induced toxicity, and one explored drug overdose. This research project revealed that most of the drug-related toxicological studies conducted in Saudi Arabia were observational studies of moderate quality. Future studies should focus on the quality of the design and reporting.

Indexed as

drugoverdosesubstancetoxictoxicology

Identifiers

PMID37082486
PMCPMC10112933

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.