Evidence map›Paper›PMID 37086282›Full record

ArticleApplied microbiology and biotechnology2023

Peptide extract from spent yeast improves resistance of Saccharomyces cerevisiae to oxidative stress.

Ana Lopes, João Azevedo-Silva, Erdem Carsanba, Manuela Pintado, Ana Sofia Oliveira, Carlos Ferreira, Joana Odila Pereira, Ana P Carvalho, Carla Oliveira

Open access · hybridAbstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ana LopesAmyris BioProducts Portugal, Unipessoal, Lda. Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.ORCID http://orcid.org/0000-0003-2858-0214
João Azevedo-SilvaUniversidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.ORCID http://orcid.org/0000-0003-1754-9254
Erdem CarsanbaAmyris BioProducts Portugal, Unipessoal, Lda. Rua Diogo Botelho 1327, 4169-005, Porto, Portugal. carsanba@amyris.com.ORCID http://orcid.org/0000-0002-7218-5070
Manuela PintadoUniversidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.ORCID http://orcid.org/0000-0002-0760-3184
Ana Sofia OliveiraUniversidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.ORCID http://orcid.org/0000-0002-4373-9804
Carlos FerreiraAmyris BioProducts Portugal, Unipessoal, Lda. Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.ORCID http://orcid.org/0000-0002-0968-5574
Joana Odila PereiraAmyris BioProducts Portugal, Unipessoal, Lda. Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.ORCID http://orcid.org/0000-0003-0300-5635
Ana P CarvalhoUniversidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.ORCID http://orcid.org/0000-0001-5967-4200
Carla OliveiraUniversidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005, Porto, Portugal. cmoliveira@ucp.pt.ORCID http://orcid.org/0000-0001-5006-3008
Universidade Católica Portuguesa · PTUniversidade do Porto · PT

Funding

European Regional Development Fund POCI-01-0247-FEDER-027578
6 · The paper itself

Abstract

Yeast cells face various stress factors during industrial fermentations, since they are exposed to harsh environmental conditions, which may impair biomolecules productivity and yield. In this work, the use of an antioxidant peptide extract obtained from industrial spent yeast was explored as supplement for Saccharomyces cerevisiae fermentation to prevent a common bottleneck: oxidative stress. For that, a recombinant yeast strain, producer of β-farnesene, was firstly incubated with 0.5 and 0.7 g/L peptide extract, in the presence and absence of hydrogen peroxide (an oxidative stress inducer), for 1-5 h, and then assayed for intracellular reactive oxygen species, and growth ability in agar spot assays. Results showed that under 2 mM H

Indexed as

AntioxidantsSaccharomyces cerevisiaeFermentationHydrogen PeroxideOxidative StressPeptidesPlant ExtractsReactive Oxygen SpeciesAntioxidantsHydrogen PeroxidePeptidesPlant ExtractsReactive Oxygen SpeciesAntioxidant activityBioreactor fermentationCircular economyFarnesene productionPeptide-rich extractReactive oxygen species

Identifiers

PMID37086282
PMCPMC10175367
OpenAlexW4366742372

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.