Evidence map›Paper›PMID 37090515›Full record

ArticlebioRxiv : the preprint server for biology2023

The time integral of BMP signaling determines fate in a stem cell model for early human development.

Seth Teague, Gillian Primavera, Bohan Chen, Emily Freeburne, Hina Khan, Kyoung Jo, Craig Johnson, Idse Heemskerk

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Seth TeagueDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan.
Gillian PrimaveraDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan.
Bohan ChenDepartment of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, Michigan.
Emily FreeburneDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan.
Hina KhanDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan.
Kyoung JoDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan.
Craig JohnsonDepartment of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan.
Idse HeemskerkDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan.
University of Michigan · US

Funding

Multifunctional morphogens: patterning precision and mesoderm migrationR35GM138346 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEEMSKERK, IDSE JOANNES · 2020 to 2025
$4.3M
Cellular Biotechnology Training Program (CBTP) - Years 31-35T32GM145304 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Guizhi Zhu · 2022 to 2026
$2.6M
NIGMS NIH HHS R35 GM138346NIGMS NIH HHS T32 GM145304
6 · The paper itself

Abstract

How paracrine signals are interpreted to yield multiple cell fate decisions in a dynamic context during human development

Identifiers

PMID37090515
PMCPMC10120633
OpenAlexW4363678782

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.