Evidence map›Paper›PMID 37091679›Full record

ArticleFrontiers in cellular and infection microbiology2023

Comparative transcriptomes reveal pro-survival and cytotoxic programs of mucosal-associated invariant T cells upon Bacillus Calmette-Guérin stimulation.

Manju Sharma, Liang Niu, Xiang Zhang, Shouxiong Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Manju SharmaDepartment of Environmental and Public Health Sciences, College of Medicine, University of Cincinnati, Cincinnati, OH, United States.
Liang NiuDepartment of Environmental and Public Health Sciences, College of Medicine, University of Cincinnati, Cincinnati, OH, United States.
Xiang ZhangDepartment of Environmental and Public Health Sciences, College of Medicine, University of Cincinnati, Cincinnati, OH, United States.
Shouxiong HuangDepartment of Environmental and Public Health Sciences, College of Medicine, University of Cincinnati, Cincinnati, OH, United States.
University of Cincinnati Medical Center · US

Funding

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI PINNEY, SUSAN MENGEL · 1992 to 2022
$35.4M
Antigen metabolomics for mucosal-associated invariant T cells in tuberculosisR21AI115358 · NIAID · UNIVERSITY OF CINCINNATI · PI HUANG, SHOUXIONG · 2015 to 2016
$435k
NIAID NIH HHS R21 AI115358NIEHS NIH HHS P30 ES006096
6 · The paper itself

Abstract

Mucosal-associated invariant T (MAIT) cells are protective against tuberculous and non-tuberculous mycobacterial infections with poorly understood mechanisms. Despite an innate-like nature, MAIT cell responses remain heterogeneous in bacterial infections. To comprehensively characterize MAIT activation programs responding to different bacteria, we stimulated MAIT cells with

Indexed as

Antineoplastic AgentsMucosal-Associated Invariant T CellsMycobacterium bovisTuberculosisBCG VaccineEscherichia coliHumansTranscriptomeAntineoplastic AgentsBCG VaccineBacillus Calmette-Guérin (BCG)MHC-related protein 1 (MR1)mucosal-associated invariant T (MAIT) cellsMycobacterium tuberculosis (M. tuberculosis)transcriptome

Identifiers

PMID37091679
PMCPMC10116416
OpenAlexW4362667798

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.