Evidence map›Paper›PMID 37098418›Full record

ArticleFood microbiology2023

Edible alginate-based films with anti-SARS-CoV-2 activity.

Miguel A Cerqueira, Ana Catarina C O Leite, Ana L Tomás, Anna Reichel, Patrícia M Silva, Nuno C Santos, Michele Michelin, Pablo Fuciños, Lorenzo M Pastrana

Abstract read
In one paragraph

Article in Food microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Miguel A CerqueiraInternational Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330, Braga, Portugal. Electronic address: miguel.cerqueira@inl.int.
Ana Catarina C O LeiteInternational Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330, Braga, Portugal.
Ana L TomásInstituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028, Lisbon, Portugal.
Anna ReichelInstituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028, Lisbon, Portugal.
Patrícia M SilvaInstituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028, Lisbon, Portugal.
Nuno C SantosInstituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028, Lisbon, Portugal.
Michele MichelinCentre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal; LABBELS - Associate Laboratory, Braga, Guimarães, Portugal.
Pablo FuciñosInternational Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330, Braga, Portugal.
Lorenzo M PastranaInternational Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330, Braga, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The viability of SARS-CoV-2 on food surfaces and its propagation through the food chain has been discussed by several stakeholders, as it may represent a serious public health problem, bringing new challenges to the food system. This work shows for the first time that edible films can be used against SARS-CoV-2. Sodium alginate-based films containing gallic acid, geraniol, and green tea extract were evaluated in terms of their antiviral activity against SARS-CoV-2. The results showed that all these films have strong in vitro antiviral activity against this virus. However, a higher concentration of the active compound (1.25%) is needed for the film containing gallic acid to achieve similar results to those obtained for lower concentrations of geraniol and green tea extract (0.313%). Furthermore, critical concentrations of the active compounds in the films were used to evaluate their stability during storage. Results showed that gallic acid-loaded films lose their activity from the second week of storage, while films with geraniol and green tea extract only show a drop in activity after four weeks. These results highlight the possibility of using edible films and coatings as antiviral materials on food surfaces or food contact materials, which may help to reduce the spreading of viruses through the food chain.

Indexed as

COVID-19Edible FilmsAcyclic MonoterpenesAlginatesAntioxidantsAntiviral AgentsFood PackagingGallic AcidHumansPlant ExtractsSARS-CoV-2TeaAcyclic MonoterpenesAlginatesAntioxidantsAntiviral AgentsGallic AcidgeraniolPlant ExtractsTeaActive filmAntiviralEdible coatingPackagingSARS-CoV-2Shelf-life

Identifiers

PMID37098418
PMCPMC9995353

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.