Evidence map›Paper›PMID 37103014›Full record

ReviewJournal of cardiovascular development and disease2023

Dual Antiplatelet Therapy and Cancer; Balancing between Ischemic and Bleeding Risk: A Narrative Review.

Grigorios Tsigkas, Angeliki Vakka, Anastasios Apostolos, Eleni Bousoula, Nikolaos Vythoulkas-Biotis, Eleni-Evangelia Koufou, Georgios Vasilagkos, Ioannis Tsiafoutis, Michalis Hamilos, Adel Aminian and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Antithrombotic Therapy in Percutaneous Atrial Structural Interventions.Journal of cardiovascular development and disease · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Grigorios TsigkasDepartment of Cardiology, University Hospital of Patras, 265 04 Patras, Greece.ORCID 0000-0002-2779-0765
Angeliki VakkaDepartment of Cardiology, University Hospital of Patras, 265 04 Patras, Greece.ORCID 0000-0003-2332-4799
Anastasios ApostolosDepartment of Cardiology, University Hospital of Patras, 265 04 Patras, Greece.ORCID 0000-0003-2616-7952
Eleni BousoulaDepartment of Cardiology, Tzaneio General Hospital, 185 36 Piraeus, Greece.
Nikolaos Vythoulkas-BiotisDepartment of Cardiology, University Hospital of Patras, 265 04 Patras, Greece.ORCID 0009-0002-4217-3922
Eleni-Evangelia KoufouDepartment of Cardiology, University Hospital of Patras, 265 04 Patras, Greece.ORCID 0000-0001-8979-8554
Georgios VasilagkosDepartment of Cardiology, University Hospital of Patras, 265 04 Patras, Greece.ORCID 0000-0001-8256-2928
Ioannis TsiafoutisFirst Department of Cardiology, Red Cross Hospital, 115 26 Athens, Greece.
Michalis HamilosDepartment of Cardiology, Heraklion University Hospital, 715 00 Heraklion, Crete, Greece.
Adel AminianDepartment of Cardiology, Centre Hospitalier Universitaire de Charleroi, 6042 Charleroi, Belgium.ORCID 0000-0002-4667-9181
Periklis DavlourosDepartment of Cardiology, University Hospital of Patras, 265 04 Patras, Greece.
General University Hospital of Patras · GRGrand Charleroi Hospital · BENational and Kapodistrian University of Athens · GRRed Cross Hospital · GRTzaneion General Hospital · GRUniversity Hospital of Heraklion · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular (CV) events in patients with cancer can be caused by concomitant CV risk factors, cancer itself, and anticancer therapy. Since malignancy can dysregulate the hemostatic system, predisposing cancer patients to both thrombosis and hemorrhage, the administration of dual antiplatelet therapy (DAPT) to patients with cancer who suffer from acute coronary syndrome (ACS) or undergo percutaneous coronary intervention (PCI) is a clinical challenge to cardiologists. Apart from PCI and ACS, other structural interventions, such as TAVR, PFO-ASD closure, and LAA occlusion, and non-cardiac diseases, such as PAD and CVAs, may require DAPT. The aim of the present review is to review the current literature on the optimal antiplatelet therapy and duration of DAPT for oncologic patients, in order to reduce both the ischemic and bleeding risk in this high-risk population.

Indexed as

acute coronary syndrome (ACS)atrial fibrillation (AF)cancercardiotoxicitydual antiplatelet therapy (DAPT)percutaneous coronary intervention (PCI)triple antithrombotic therapy (TAT)

Identifiers

PMID37103014
PMCPMC10144375
OpenAlexW4360857220

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.