Evidence map›Paper›PMID 37103351›Full record

ReviewMarine drugs2023

Marine-Inspired Approaches as a Smart Tool to Face Osteochondral Regeneration.

Anna Tampieri, Elizaveta Kon, Monica Sandri, Elisabetta Campodoni, Massimiliano Dapporto, Simone Sprio

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anna TampieriInstitute of Science, Technology and Sustainability for Ceramics, ISSMC-CNR (Former ISTEC-CNR), 40129 Faenza, Italy.
Elizaveta KonHumanitas Research Hospital, 20089 Rozzano, Italy.ORCID 0000-0003-0649-2336
Monica SandriInstitute of Science, Technology and Sustainability for Ceramics, ISSMC-CNR (Former ISTEC-CNR), 40129 Faenza, Italy.ORCID 0000-0001-5782-3137
Elisabetta CampodoniInstitute of Science, Technology and Sustainability for Ceramics, ISSMC-CNR (Former ISTEC-CNR), 40129 Faenza, Italy.ORCID 0000-0001-8931-2921
Massimiliano DapportoInstitute of Science, Technology and Sustainability for Ceramics, ISSMC-CNR (Former ISTEC-CNR), 40129 Faenza, Italy.
Simone SprioInstitute of Science, Technology and Sustainability for Ceramics, ISSMC-CNR (Former ISTEC-CNR), 40129 Faenza, Italy.ORCID 0000-0003-1526-7915
Institute of Science and Technology for Ceramics · ITIRCCS Humanitas Research Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The degeneration of osteochondral tissue represents one of the major causes of disability in modern society and it is expected to fuel the demand for new solutions to repair and regenerate the damaged articular joints. In particular, osteoarthritis (OA) is the most common complication in articular diseases and a leading cause of chronic disability affecting a steady increasing number of people. The regeneration of osteochondral (OC) defects is one of the most challenging tasks in orthopedics since this anatomical region is composed of different tissues, characterized by antithetic features and functionalities, in tight connection to work together as a joint. The altered structural and mechanical joint environment impairs the natural tissue metabolism, thus making OC regeneration even more challenging. In this scenario, marine-derived ingredients elicit ever-increased interest for biomedical applications as a result of their outstanding mechanical and multiple biologic properties. The review highlights the possibility to exploit such unique features using a combination of bio-inspired synthesis process and 3D manufacturing technologies, relevant to generate compositionally and structurally graded hybrid constructs reproducing the smart architecture and biomechanical functions of natural OC regions.

Indexed as

Cartilage, ArticularOsteoarthritisHumansTissue EngineeringTissue Scaffolds3D printingapatitesfucoidanshybrid materialsmarine-derived ingredientsmutable collagenosteochondral scaffold

Identifiers

PMID37103351
PMCPMC10145639
OpenAlexW4361215301

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.