Evidence map›Paper›PMID 37107924›Full record

ArticleHealthcare (Basel, Switzerland)2023

Evaluating the Feasibility of Pro-Neurotensin and 25-Hydroxyvitamin D3 as Possible Indicators for Type 2 Diabetes Mellitus and Its Complications.

Amal A Mohammed, Dina M Abo El-Matty, Esraa A Abd ElSalam, Mona A Hussein, Wael Hafez, Sharehan A Ibrahim, Eman A H Shaheen, Eman A Awad, Marwa A Osman, Marwa S Abd El-Raouf and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Recent Updates on Diabetes and Bone.International journal of molecular sciences · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 2 countries.

Amal A MohammedDepartment of Biochemistry and Molecular Biology, National Hepatology and Tropical Medicine Research Institute (NHTMRI), Cairo 11796, Egypt.
Dina M Abo El-MattyDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Esraa A Abd ElSalamDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Mona A HusseinDepartment of Internal Medicine, National Institute of Diabetes and Endocrinology, Cairo 11562, Egypt.
Wael HafezDepartment of Internal Medicine, The National Research Centre, Cairo 11511, Egypt.ORCID 0000-0003-1203-0808
Sharehan A IbrahimDepartment of Internal Medicine, Faculty of Medicine, Minia University, Minya 61511, Egypt.
Eman A H ShaheenDepartment of Clinical and Chemical Pathology, Faculty of Medicine, Helwan University, Cairo 11795, Egypt.
Eman A AwadDepartment of Internal Medicine, Faculty of Medicine for Girls, Al-Azhar University, Cairo 11795, Egypt.
Marwa A OsmanDepartment of Neurology, Faculty of Medicine for Girls, Al-Azhar University, Cairo 11884, Egypt.
Marwa S Abd El-RaoufDepartment of Public Health, Faculty of Medicine, Benha University, Benha 13511, Egypt.
Salma M SaedDepartment of Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Cairo 11566, Egypt.
Reham Y El-AmirDepartment of Public Health, Faculty of Medicine, Cairo University, Giza 12211, Egypt.
Doaa GhaithDepartment of Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Cairo 11566, Egypt.
Fatme Al AnoutiDepartment of Health Sciences, College of Natural and Health Sciences, Zayed University, Abu Dhabi 144534, United Arab Emirates.ORCID 0000-0002-1993-6656
Alaa S WahbaDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0002-2600-9965
Cairo University · EGSuez Canal University · EGAl-Azhar University · EGBenha University · EGHelwan University · EGMinia University · EGNational Research Centre · EGNational Water Research Center · EGZayed University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Type 2 diabetes mellitus (T2DM) and metabolic syndrome are associated with decreased vitamin D. In contrast, high pro-neurotensin (pro-NT) levels are linked with an increased risk of T2DM and cardiovascular disease. We aimed to determine the validity of pro-NT and 25-dihydroxy vitamin D3 levels as predictors for T2DM complications; (2) Methods: One hundred T2DM, and one hundred healthy volunteers participated in this case-control study. Their Pro-NT and 25-hydroxyvitamin D3 levels were evaluated using the ELISA technique; (3) Results: Pro-NT and 25 (OH) vitamin D3 have significant validity and accuracy in T2DM prediction, 84.5%, and 90.5%, respectively (

Indexed as

25 (OH) Vit D3insulin resistancemarkerPro-NTT2DM

Identifiers

PMID37107924
PMCPMC10138095
OpenAlexW4365146699

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.