Evidence map›Paper›PMID 37108125›Full record

ReviewInternational journal of molecular sciences2023

How Can We Prevent Mother-to-Child Transmission of HTLV-1?

Kazuo Itabashi, Tokuo Miyazawa, Kaoru Uchimaru

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. The Interactions between Cells and Viruses.International journal of molecular sciences · 2024
    Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kazuo ItabashiAiseikai-Memorial Ibaraki Welfare and Medical Center, Ibaraki 3100836, Japan.ORCID 0000-0003-1270-6871
Tokuo MiyazawaDepartment of Pediatrics, Showa University School of Medicine, Tokyo 1428666, Japan.
Kaoru UchimaruDepartment of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo 1088639, Japan.
Showa University · JPUniversity of Tokyo Hospital · JP

Funding

Ministry of Health, Labour and Welfare (MHLW): Health Research on Children, Youth, and Families JPMH20DA1007
6 · The paper itself

Abstract

The perception of human T-cell leukemia virus type 1 (HTlV-1) infection as a "silent disease" has recently given way to concern that its presence may be having a variety of effects. HTLV-1 is known to cause adult T-cell leukemia (ATL), an aggressive cancer of peripheral CD4 T cells; however, it is also responsible for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Most patients develop ATL as a result of HTLV-1 mother-to-child transmission. The primary route of mother-to-child transmission is through the mother's milk. In the absence of effective drug therapy, total artificial nutrition such as exclusive formula feeding is a reliable means of preventing mother-to-child transmission after birth, except for a small percentage of prenatal infections. A recent study found that the rate of mother-to-child transmission with short-term breastfeeding (within 90 days) did not exceed that of total artificial nutrition. Because these preventive measures are in exchange for the benefits of breastfeeding, clinical applications of antiretroviral drugs and immunotherapy with vaccines and neutralizing antibodies are urgently needed.

Indexed as

Human T-lymphotropic virus 1Leukemia-Lymphoma, Adult T-CellParaparesis, Tropical SpasticAdultCD4-Positive T-LymphocytesFemaleHumansInfectious Disease Transmission, VerticalPregnancyadult T-cell leukemia (ATL)antenatal screeninghuman T-cell leukemia virus type 1 (HTlV-1)mother-to-child transmissionnutritional regimensprevention

Identifiers

PMID37108125
PMCPMC10138424
OpenAlexW4363676856

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.