Evidence map›Paper›PMID 37108387›Full record

ArticleInternational journal of molecular sciences2023

Essential Oils from Mediterranean Plants Inhibit In Vitro Monocyte Adhesion to Endothelial Cells from Umbilical Cords of Females with Gestational Diabetes Mellitus.

Valeria Schiavone, Tea Romasco, Nadia Di Pietrantonio, Stefania Garzoli, Carola Palmerini, Pamela Di Tomo, Caterina Pipino, Domitilla Mandatori, Rossella Fioravanti, Elena Butturini and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Valeria SchiavoneDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Tea RomascoDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-4868-3838
Nadia Di PietrantonioDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0001-6604-0804
Stefania GarzoliDepartment of Pharmaceutical Chemistry and Technology, Sapienza University of Rome, 00185 Roma, Italy.ORCID 0000-0001-8535-0533
Carola PalmeriniDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Pamela Di TomoDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0003-1995-3306
Caterina PipinoDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-4350-8686
Domitilla MandatoriDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Rossella FioravantiDepartment of Pharmaceutical Chemistry and Technology, Sapienza University of Rome, 00185 Roma, Italy.
Elena ButturiniDepartment of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37129 Verona, Italy.
Manuela SabatinoRome Center for Molecular Design-RCMD, Department of Pharmaceutical Chemistry and Technology, Sapienza University of Rome, 00185 Roma, Italy.ORCID 0000-0001-9127-3925
Maria Pompea Antonia BaldassarreCenter for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-9707-7439
Rino RagnoRome Center for Molecular Design-RCMD, Department of Pharmaceutical Chemistry and Technology, Sapienza University of Rome, 00185 Roma, Italy.ORCID 0000-0001-5399-975X
Assunta PandolfiDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0003-4135-7631
Natalia Di PietroDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0001-9720-2116
University of Chieti-Pescara · ITSapienza University of Rome · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential oils (EOs) are mixtures of volatile compounds belonging to several chemical classes derived from aromatic plants using different distillation techniques. Recent studies suggest that the consumption of Mediterranean plants, such as anise and laurel, contributes to improving the lipid and glycemic profile of patients with diabetes mellitus (DM). Hence, the aim of the present study was to investigate the potential anti-inflammatory effect of anise and laurel EOs (AEO and LEO) on endothelial cells isolated from the umbilical cord vein of females with gestational diabetes mellitus (GDM-HUVEC), which is a suitable in vitro model to reproduce the pro-inflammatory phenotype of a diabetic endothelium. For this purpose, the Gas Chromatographic/Mass Spectrometric (GC-MS) chemical profiles of AEO and LEO were first analyzed. Thus, GDM-HUVEC and related controls (C-HUVEC) were pre-treated for 24 h with AEO and LEO at 0.025%

Indexed as

Diabetes, GestationalOils, VolatileCell AdhesionEndothelial CellsFemaleHumansIntercellular Adhesion Molecule-1MonocytesNF-kappa BPregnancyTumor Necrosis Factor-alphaU937 CellsUmbilical CordVascular Cell Adhesion Molecule-1Intercellular Adhesion Molecule-1NF-kappa BOils, VolatileTumor Necrosis Factor-alphaVascular Cell Adhesion Molecule-1aniseanti-inflammatorydiabetesendothelial dysfunctionessential oilsHUVECinflammationlaurelNF-κB p65VCAM-1

Identifiers

PMID37108387
PMCPMC10138528
OpenAlexW4365515163

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.