Evidence map›Paper›PMID 37108490›Full record

ArticleInternational journal of molecular sciences2023

Sensory Neurons, PIEZO Channels and PAC1 Receptors Regulate the Mechanosensitive Release of Soluble Ectonucleotidases in the Murine Urinary Bladder Lamina Propria.

Mafalda S L Aresta Branco, Alejandro Gutierrez Cruz, Mahsa Borhani Peikani, Violeta N Mutafova-Yambolieva

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mafalda S L Aresta BrancoDepartment of Physiology and Cell Biology, School of Medicine, University of Nevada, Reno, NV 89557, USA.ORCID 0000-0001-5210-9137
Alejandro Gutierrez CruzDepartment of Physiology and Cell Biology, School of Medicine, University of Nevada, Reno, NV 89557, USA.
Mahsa Borhani PeikaniDepartment of Physiology and Cell Biology, School of Medicine, University of Nevada, Reno, NV 89557, USA.
Violeta N Mutafova-YambolievaDepartment of Physiology and Cell Biology, School of Medicine, University of Nevada, Reno, NV 89557, USA.ORCID 0000-0003-2519-3323
University of Nevada, Reno · US

Funding

Urothelial Purinergic Signaling During Bladder FillingR01DK119482 · NIDDK · UNIVERSITY OF NEVADA RENO · PI Violeta N. Mutafova-Yambolieva · 2020 to 2026
$3.3M
NIDDK NIH HHS DK 119482NIDDK NIH HHS R01 DK119482
6 · The paper itself

Abstract

The urinary bladder requires adequate concentrations of extracellular adenosine 5'-triphosphate (ATP) and other purines at receptor sites to function properly. Sequential dephosphorylation of ATP to ADP, AMP and adenosine (ADO) by membrane-bound and soluble ectonucleotidases (s-ENTDs) is essential for achieving suitable extracellular levels of purine mediators. S-ENTDs, in particular, are released in the bladder suburothelium/lamina propria (LP) in a mechanosensitive manner. Using 1,N

Indexed as

Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type IUrinary BladderAdenosineAnimalsIon ChannelsMiceMucous MembranePituitary Adenylate Cyclase-Activating PolypeptideSensory Receptor CellsUrotheliumAdenosineIon ChannelsPituitary Adenylate Cyclase-Activating PolypeptideReceptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type IATPbladderbladder lamina propriaectonucleotidasesPAC1 receptorPACAPPIEZOpurinergicsensory neuropeptidesurothelium

Identifiers

PMID37108490
PMCPMC10138949
OpenAlexW4366090643

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.