Evidence map›Paper›PMID 37108555›Full record

ArticleInternational journal of molecular sciences2023

Innova 2020: A Follow-Up Study of the Fecal Microbiota of Infants Using a Novel Infant Formula between 6 Months and 12 Months of Age.

Julio Plaza-Diaz, Francisco Javier Ruiz-Ojeda, Javier Morales, Rafael Martín-Masot, Eric Climent, Ángela Silva, Juan F Martinez-Blanch, María Enrique, Marta Tortajada, Daniel Ramon and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 3 countries.

Julio Plaza-DiazDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-5171-9408
Francisco Javier Ruiz-OjedaDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-4452-0855
Javier MoralesProduct Development Department, Alter Farmacia SA, 28880 Madrid, Spain.
Rafael Martín-MasotInstitute of Nutrition and Food Technology "José Mataix", Centre of Biomedical Research, University of Granada, Avda. del Conocimiento s/n. Armilla, 18016 Granada, Spain.ORCID 0000-0003-0113-9904
Eric ClimentADM-BIOPOLIS, Scientific Park Universitat de València, 46980 València, Spain.ORCID 0000-0001-6372-8371
Ángela SilvaADM-BIOPOLIS, Scientific Park Universitat de València, 46980 València, Spain.
Juan F Martinez-BlanchADM-BIOPOLIS, Scientific Park Universitat de València, 46980 València, Spain.ORCID 0000-0002-8419-7909
María EnriqueADM-BIOPOLIS, Scientific Park Universitat de València, 46980 València, Spain.
Marta TortajadaADM-BIOPOLIS, Scientific Park Universitat de València, 46980 València, Spain.
Daniel RamonADM-BIOPOLIS, Scientific Park Universitat de València, 46980 València, Spain.
Beatriz AlvarezADM-BIOPOLIS, Scientific Park Universitat de València, 46980 València, Spain.
Empar ChenollADM-BIOPOLIS, Scientific Park Universitat de València, 46980 València, Spain.ORCID 0000-0002-6891-3573
Ángel GilDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-7663-0939
Universitat de València · ESUniversidad de Granada · ES

Funding

Alter Farmacia S. A INNOVA2020
6 · The paper itself

Abstract

The World Health Organization recommends exclusive breastfeeding on demand until at least the sixth month of life. Breast milk or infant formula is the infant's primary food source until the age of one year, followed by the gradual introduction of other foods. During weaning, the intestinal microbiota evolves to a profile close to that of the adult, and its disruption can result in an increased incidence of acute infectious diseases. We aimed to determine whether a novel starting formula (INN) provides gut microbiota compositions more similar to those of breastfed (BF) infants from 6 to 12 months of age compared to a standard formula (STD). This study included 210 infants (70 per group) who completed the intervention until they reached the age of 12 months. In the intervention period, infants were divided into three groups. Group 1 received an INN formula with a lower protein content, a casein to whey protein ratio of approximately 70/30, twice as much docosahexaenoic acid as the STD formula, a thermally inactivated postbiotic (

Indexed as

Gastrointestinal MicrobiomeInfant FormulaBreast FeedingEscherichia coliFecesFemaleFollow-Up StudiesHumansInfantMilk, Humanarachidonic acidBifidobacterium animalis subsp. lactisbody compositionBPL1TMdocosahexaenoic acidinfant formulapostbioticsα-lactalbumin

Identifiers

PMID37108555
PMCPMC10139017
OpenAlexW4366188170

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.