Evidence map›Paper›PMID 37109161›Full record

ArticleJournal of clinical medicine2023

Vitamin D, Albumin, and D-Dimer as Significant Prognostic Markers in Early Hospitalization in Patients with COVID-19.

Biljana Popovska Jovičić, Ivana Raković, Jagoda Gavrilović, Sofija Sekulić Marković, Sara Petrović, Vladan Marković, Aleksandar Pavković, Predrag Čanović, Ružica Radojević Marjanović, Violeta Irić-Čupić and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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  7. What Is the Impact of Baseline Inflammatory and Hemostatic Indicators with the Risk of Mortality in Severe Inpatients with COVID-19: A Retrospective Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Biljana Popovska JovičićDepartment of Infectious Diseases, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0001-9280-2251
Ivana RakovićDepartment of Infectious Diseases, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Jagoda GavrilovićDepartment of Infectious Diseases, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Sofija Sekulić MarkovićDepartment of Infectious Diseases, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Sara PetrovićDepartment of Infectious Diseases, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Vladan MarkovićDepartment of Radiology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Aleksandar PavkovićDepartment of Radiological Diagnostics, University Clinical Center Kragujevac, 34000 Kragujevac, Serbia.
Predrag ČanovićDepartment of Infectious Diseases, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Ružica Radojević MarjanovićClinic for Infectious Diseases, University Clinical Center Kragujevac, Zmaj Jovina 30, 34000 Kragujevac, Serbia.
Violeta Irić-ČupićDepartment of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Lidija Popović DragonjićUniversity of Niš, Faculty of Medicine in Nis, Cathedra for Infectious Diseases and Epidemiology, Blvd. Dr Zorana Djindjica 81, 18000 Niš, Serbia.
Miloš Z MilosavljevićDepartment of Pathology, University Clinical Center Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0003-4201-0269
University of Kragujevac · RSClinical Centre of Kragujevac · RSUniversity of Nis · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 continues to pose a major challenge to scientists and clinicians. We examined the significance of the serum concentrations of vitamin D, albumin, and D-dimer for the severity of the clinical picture and mortality in COVID-19. MATERIALS AND

methodsA total of 288 patients treated for COVID-19 infection participated in the research. The patients were treated in the period from May 2020 to January 2021. All patients were divided based on the need for oxygen therapy (Sat > 94%) into patients with mild or severe clinical pictures. The biochemical and radiographic parameters of the patients were analyzed. Appropriate statistical methods were used in the statistical analysis.

resultsIn patients with COVID-19 with confirmed severe clinical pictures, lower values of serum albumin (

conclusionThe significance of the predictive parameters in our study indicates the existence of an important combined role of vitamin D, albumin, and D-dimer in the early diagnosis of the most severe patients suffering from COVID-19. Reduced values of vitamin D and albumin, in combination with elevated values of D-dimer, can be timely indicators of the development of a severe clinical picture and death due to COVID-19.

Indexed as

albuminCOVID-19D-dimerlethal outcomeSARS-CoV-2severity of illnessvitamin D

Identifiers

PMID37109161
PMCPMC10145116
OpenAlexW4365145858

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.