Evidence mapPaperPMID 37109166Full record

ArticleJournal of clinical medicine2023

Maternal Preconception Body Mass Index Overtakes Age as a Risk Factor for Gestational Diabetes Mellitus.

Maria Mirabelli, Vera Tocci, Alessandra Donnici, Stefania Giuliano, Paola Sarnelli, Alessandro Salatino, Marta Greco, Luigi Puccio, Eusebio Chiefari, Daniela Patrizia Foti and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Maria MirabelliDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-6427-7186
Vera TocciDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-9241-1848
Alessandra DonniciOperative Unit of Endocrinology, "Mater Domini" University Hospital, 88100 Catanzaro, Italy.
Stefania GiulianoOperative Unit of Endocrinology, "Mater Domini" University Hospital, 88100 Catanzaro, Italy.
Paola SarnelliOperative Unit of Endocrinology, "Pugliese Ciaccio" Hospital, 88100 Catanzaro, Italy.
Alessandro SalatinoDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.
Marta GrecoDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-4192-3891
Luigi PuccioOperative Unit of Endocrinology, "Pugliese Ciaccio" Hospital, 88100 Catanzaro, Italy.
Eusebio ChiefariDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.
Daniela Patrizia FotiDepartment of Experimental and Clinical Medicine, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-9536-5736
Antonio BrunettiDepartment of Health Sciences, University "Magna Græcia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-1533-8779
Magna Graecia University · ITAzienda Ospedaliera Pugliese Ciaccio · ITAzienda Ospedaliero Universitario Mater Domini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction-The purpose of this study was to determine the relative impact of modifiable and non-modifiable risk factors in the development of gestational diabetes mellitus (GDM), with a particular focus on maternal preconception body mass index (BMI) and age, two important determinants of insulin resistance. Understanding the factors that contribute most to the current escalation of GDM rates in pregnant women could help to inform prevention and intervention strategies, particularly in areas where this female endocrine disorder has an elevated prevalence. Methods-A retrospective, contemporary, large population of singleton pregnant women from southern Italy who underwent 75 g OGTT for GDM screening was enrolled at the Endocrinology Unit, "Pugliese Ciaccio" Hospital, Catanzaro. Relevant clinical data were collected, and the characteristics of women diagnosed with GDM or with normal glucose tolerance were compared. The effect estimates of maternal preconception BMI and age as risk factors for GDM development were calculated through correlation and logistic regression analysis by adjusting for potential confounders. Results-Out of the 3856 women enrolled, 885 (23.0%) were diagnosed with GDM as per IADPSG criteria. Advanced maternal age (≥35 years), gravidity, reproductive history of spontaneous abortion(s), previous GDM, and thyroid and thrombophilic diseases, all emerged as non-modifiable risk factors of GDM, whereas preconception overweight or obesity was the sole potentially modifiable risk factor among those investigated. Maternal preconception BMI, but not age, had a moderate positive association with fasting glucose levels at the time of 75 g OGTT (Pearson coefficient: 0.245,

Indexed as

advanced maternal agebody mass indexgestational diabetes riskinsulin resistanceobesity

Identifiers

PMID37109166
PMCPMC10145909
OpenAlexW4365453838

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.