Evidence map›Paper›PMID 37109471›Full record

ArticleLife (Basel, Switzerland)2023

Insight into Elderly ALS Patients in the Emilia Romagna Region: Epidemiological and Clinical Features of Late-Onset ALS in a Prospective, Population-Based Study.

Giulia Gianferrari, Ilaria Martinelli, Cecilia Simonini, Elisabetta Zucchi, Nicola Fini, Maria Caputo, Andrea Ghezzi, Annalisa Gessani, Elena Canali, Mario Casmiro and 21 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 14 institutions in 2 countries.

Giulia GianferrariDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-4260-0915
Ilaria MartinelliDepartment of Neurosciences, Azienda Ospedaliero Universitaria di Modena, 41124 Modena, Italy.ORCID 0000-0003-2566-3671
Cecilia SimoniniDepartment of Neurosciences, Azienda Ospedaliero Universitaria di Modena, 41124 Modena, Italy.ORCID 0000-0001-5456-2365
Elisabetta ZucchiDepartment of Neurosciences, Azienda Ospedaliero Universitaria di Modena, 41124 Modena, Italy.
Nicola FiniDepartment of Neurosciences, Azienda Ospedaliero Universitaria di Modena, 41124 Modena, Italy.
Maria CaputoDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Andrea GhezziDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Annalisa GessaniDepartment of Neurosciences, Azienda Ospedaliero Universitaria di Modena, 41124 Modena, Italy.
Elena CanaliDepartment of Neurology, IRCCS Arcispedale Santa Maria Nuova, 42123 Reggio Emilia, Italy.
Mario CasmiroDepartment of Neurology, Faenza and Ravenna Hospital, 48100 Ravenna, Italy.
Patrizia De MassisDepartment of Neurology, Imola Hospital, 40026 Bologna, Italy.ORCID 0000-0001-9713-7721
Marco Curro' DossiDepartment of Neurology, Infermi Hospital, 48018 Rimini, Italy.
Silvia De PasquaDepartment of Neurology, Carpi Hospital, 41012 Modena, Italy.
Rocco LiguoriDepartment of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-1815-1013
Marco LongoniDepartment of Neurology, Infermi Hospital, 48018 Rimini, Italy.ORCID 0000-0003-2173-4858
Doriana MediciDepartment of Neurology, Fidenza Hospital, 43036 Parma, Italy.
Simonetta MorresiDepartment of Neurology, Bufalini Hospital, 47521 Cesena, Italy.
Alberto PatuelliDepartment of Neurology, Forlì Hospital, 47121 Forlì, Italy.
Maura PugliattiDepartment of Neurosciences, University of Ferrara, 44121 Ferrara, Italy.
Mario SantangeloDepartment of Neurology, Carpi Hospital, 41012 Modena, Italy.
Elisabetta SetteDepartment of Neurology, St. Anna Hospital, 44124 Ferrara, Italy.
Filippo StragliatiDepartment of General and Specialized Medicine, University Hospital of Parma, 43126 Parma, Italy.
Emilio TerlizziDepartment of Neurology, G. Da Saliceto Hospital, 29121 Piacenza, Italy.
Veria VacchianoDepartment of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-3607-2394
Lucia ZinnoDepartment of General and Specialized Medicine, University Hospital of Parma, 43126 Parma, Italy.
Salvatore FerroDepartment of Hospital Services, Emilia Romagna Regional Health Authority, 40127 Bologna, Italy.
Amedeo AmedeiDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-6797-9343
Tommaso FilippiniDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0003-2100-0344
Marco VincetiDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-0551-2473
Errals Group
Jessica MandrioliDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-9244-9782
University of Modena and Reggio Emilia · ITAzienda Ospedaliero-Universitaria di Modena · ITIstituto delle Scienze Neurologiche di Bologna · ITOspedale “M. Bufalini” di Cesena · ITUniversity of Parma · ITBoston University · USCarlo Forlanini Hospital · ITGuglielmo da Saliceto Hospital · ITOspedale Infermi di Rimini · ITOspedale Santa Maria · ITOspedale "Santa Maria delle Croci" di Ravenna · ITOspedale Sant'Anna · ITUniversity of Ferrara · ITUniversity of Florence · IT

Funding

Emilia Romagna Regional Health Authority GPG/2022/1343
6 · The paper itself

Abstract

Few studies have focused on elderly (>80 years) amyotrophic lateral sclerosis (ALS) patients, who represent a fragile subgroup generally not included in clinical trials and often neglected because they are more difficult to diagnose and manage. We analyzed the clinical and genetic features of very late-onset ALS patients through a prospective, population-based study in the Emilia Romagna Region of Italy. From 2009 to 2019, 222 (13.76%) out of 1613 patients in incident cases were over 80 years old at diagnosis, with a female predominance (F:M = 1.18). Elderly ALS patients represented 12.02% of patients before 2015 and 15.91% from 2015 onwards (

Indexed as

amyotrophic lateral sclerosiselderly ALSepidemiologyphenotypeprognosissurvival

Identifiers

PMID37109471
PMCPMC10144747
OpenAlexW4362558780

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.