Evidence map›Paper›PMID 37110520›Full record

ArticleMolecules (Basel, Switzerland)2023

Study of the Sensing Kinetics of G Protein-Coupled Estrogen Receptor Sensors for Common Estrogens and Estrogen Analogs.

Dingqiang Lu, Xinqian Wang, Chunlei Feng, Danyang Liu, Yixuan Liu, Yujiao Liu, Jie Li, Jiayao Zhang, Na Li, Yujing Deng and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Dingqiang LuCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.ORCID 0000-0001-6364-5939
Xinqian WangCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.ORCID 0000-0002-8053-9908
Chunlei FengCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.
Danyang LiuCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.ORCID 0000-0003-3076-8662
Yixuan LiuCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.
Yujiao LiuCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.
Jie LiCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.
Jiayao ZhangCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.
Na LiCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.
Yujing DengCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.
Ke WangCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.
Ruijuan RenTianjin Institute for Food Safety Inspection Technology, Tianjin 300134, China.
Guangchang PangCollege of Biotechnology & Food Science, Tianjin University of Commerce, Tianjin 300134, China.ORCID 0000-0001-9828-4950
Tianjin University of Commerce · CNTianjin Special Equipment Supervision and Inspection Technology Research Institute · CN

Funding

The National Natural Science Foundation of China 31901782
6 · The paper itself

Abstract

Endogenous and exogenous estrogens are widely present in food and food packaging, and high levels of natural estrogens and the misuse or illegal use of synthetic estrogens can lead to endocrine disorders and even cancer in humans. Therefore, it is consequently important to accurately evaluate the presence of food-functional ingredients or toxins with estrogen-like effects. In this study, an electrochemical sensor based on G protein-coupled estrogen receptors (GPERs) was fabricated by self-assembly, modified by double-layered gold nanoparticles, and used to measure the sensing kinetics for five GPER ligands. The interconnected allosteric constants (

Indexed as

EstrogensMetal NanoparticlesBisphenol A CompoundsEstradiolGoldGTP-Binding ProteinsHumansKineticsLigandsReceptors, EstrogenReceptors, G-Protein-CoupledResveratrolbisphenol ABisphenol A CompoundsEstradiolEstrogensGoldGTP-Binding ProteinsLigandsReceptors, EstrogenReceptors, G-Protein-CoupledResveratrolelectrochemical signal amplification systemestrogensGPERinterconnect allosteric constantmolecular simulation dockingreceptor-ligand interaction

Identifiers

PMID37110520
PMCPMC10143753
OpenAlexW4362699735

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.