Evidence mapPaperPMID 37111184Full record

ArticleNutrients2023

Neonatal Leptin Levels Predict the Early Childhood Developmental Assessment Scores of Preterm Infants.

Robert D Roghair, Tarah T Colaizy, Baiba Steinbrekera, Réka A Vass, Erica Hsu, Daniel Dagle, Trassanee Chatmethakul

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Robert D RoghairDepartment of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, IA 52242, USA.ORCID 0000-0002-0321-582X
Tarah T ColaizyDepartment of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, IA 52242, USA.
Baiba SteinbrekeraDepartment of Pediatrics, University of South Dakota, Sioux Falls, SD 57105, USA.
Réka A VassDepartment of Obstetrics and Gynecology, Medical School University of Pécs, 7624 Pécs, Hungary.ORCID 0000-0002-0436-4261
Erica HsuDepartment of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, IA 52242, USA.
Daniel DagleDepartment of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, IA 52242, USA.
Trassanee ChatmethakulDepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.ORCID 0000-0002-5988-9030
University of Iowa Stead Family Children’s Hospital · USUniversity of Oklahoma Health Sciences Center · USUniversity of Pecs · HUUniversity of South Dakota · US

Funding

Stead Family Department of Pediatrics Strategic Investment
6 · The paper itself

Abstract

Preterm infants have low circulating levels of leptin, a key trophic hormone that influences growth and development. While the clinical importance of prematurity-associated leptin deficiency is undefined, recent preclinical and clinical investigations have shown that targeted enteral leptin supplementation can normalize neonatal leptin levels. We tested the hypothesis that, independent of growth velocity, prematurity-related neonatal leptin deficiency predicts adverse cardiovascular and neurodevelopmental outcomes. In a planned 2-year longitudinal follow-up of 83 preterm infants born at 22 to 32 weeks' gestation, we obtained blood pressures from 58 children and the Ages & Stages Questionnaire (ASQ-3) for 66 children. Based on univariate analysis, blood pressures correlated with gestational age at birth (R = 0.30,

Indexed as

Infant, PrematureLeptinChildChild DevelopmentChild, PreschoolFemaleGestational AgeHumansInfantInfant, NewbornMaleWeight GainLeptinbreast milkcardiovascularchild developmentdevelopmental delayhypertensionneonatologyneurodevelopmentnutritionoutcomessexually dimorphic

Identifiers

PMID37111184
PMCPMC10144252
OpenAlexW4366597730

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.