Evidence map›Paper›PMID 37112624›Full record

ReviewToxics2023

Ferroptosis as a Potential Therapeutic Target of Traditional Chinese Medicine for Mycotoxicosis: A Review.

Wenli Ding, Luxi Lin, Ke Yue, Yanfeng He, Bowen Xu, Aftab Shaukat, Shucheng Huang

Open access · goldAbstract readReview
In one paragraph

Review in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Role of ferroptosis in food-borne mycotoxin-induced toxicities.Apoptosis : an international journal on programmed cell death · 2024
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wenli DingCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Luxi LinCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Ke YueCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Yanfeng HeCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Bowen XuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Aftab ShaukatNational Center for International Research on Animal Genetics, Breeding and Reproduction (NCIRAGBR), Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0003-1670-6916
Shucheng HuangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0003-3163-8616
Henan Agricultural University · CNHuazhong Agricultural University · CN

Funding

National Natural Science Foundation of China 32202876Special Support Fund for High-level Talents of Henan Agricultural University 30501374
6 · The paper itself

Abstract

Mycotoxin contamination has become one of the biggest hidden dangers of food safety, which seriously threatens human health. Understanding the mechanisms by which mycotoxins exert toxicity is key to detoxification. Ferroptosis is an adjustable cell death characterized by iron overload and lipid reactive oxygen species (ROS) accumulation and glutathione (GSH) depletion. More and more studies have shown that ferroptosis is involved in organ damage from mycotoxins exposure, and natural antioxidants can alleviate mycotoxicosis as well as effectively regulate ferroptosis. In recent years, research on the treatment of diseases by Chinese herbal medicine through ferroptosis has attracted more attention. This article reviews the mechanism of ferroptosis, discusses the role of ferroptosis in mycotoxicosis, and summarizes the current status of the regulation of various mycotoxicosis through ferroptosis by Chinese herbal interventions, providing a potential strategy for better involvement of Chinese herbal medicine in the treatment of mycotoxicosis in the future.

Indexed as

aflatoxin B1Chinese herbsferroptosisiron metabolismlipid peroxidationmycotoxin

Identifiers

PMID37112624
PMCPMC10142935
OpenAlexW4366771095

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.