Evidence map›Paper›PMID 37117012›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Hypothalamic Supramammillary Nucleus Selectively Excites Hippocampal CA3 Interneurons to Suppress CA3 Pyramidal Neuron Activity.

Minghua Li, Jessica L Kinney, Yu-Qiu Jiang, Daniel K Lee, Qiwen Wu, Daehoon Lee, Wen-Cheng Xiong, Qian Sun

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Developmental CA2 perineuronal net reduction restores social memory inbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Dorsoventral Heterogeneity of Synaptic Connectivity in Hippocampal CA3 Pyramidal Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Minghua LiDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Jessica L KinneyDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Yu-Qiu JiangDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Daniel K LeeDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Qiwen WuDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Daehoon LeeDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Wen-Cheng XiongDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Qian SunDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106 qxs111@case.edu.
Case Western Reserve University · US

Funding

Long-range GABAergic inhibition coordinates hippocampal-subcortical circuit activity in memory formationR01MH130367 · NIMH · CASE WESTERN RESERVE UNIVERSITY · PI Qian Sun · 2023 to 2026
$2.0M
The role of subcortical inputs to the hippocampal CA3 region in fear memoryR01MH129294 · NIMH · CASE WESTERN RESERVE UNIVERSITY · PI Qian Sun · 2023 to 2026
$1.6M
Dorsoventral functional divergence of the hippocampal CA3 circuitK01MH117444 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SUN, QIAN · 2018 to 2021
$492k
NIMH NIH HHS K01 MH117444NIMH NIH HHS R01 MH129294NIMH NIH HHS R01 MH130367
6 · The paper itself

Abstract

A key mode of neuronal communication between distant brain regions is through excitatory synaptic transmission mediated by long-range glutamatergic projections emitted from principal neurons. The long-range glutamatergic projection normally forms numerous

Indexed as

InterneuronsPyramidal CellsAnimalsHippocampusHypothalamus, PosteriorMiceNeuronsCA3dentate gyrushippocampusinhibitionparvalbumin interneuronsupramammillary nucleus

Identifiers

PMID37117012
PMCPMC10286942
OpenAlexW4367309097

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.