Evidence map›Paper›PMID 37125283›Full record

ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2023

Atrial fibrillation and sympatho-vagal imbalance: from the choice of the antiarrhythmic treatment to patients with syncope and ganglionated plexi ablation.

Marco Rebecchi, Ermenegildo De Ruvo, Marianna Sgueglia, Carlo Lavalle, Stefano Canestrelli, Alessandro Politano, Ilaria Jacomelli, Paolo Golia, Cinzia Crescenzi, Lucia De Luca and 3 more

Open access · hybridAbstract read
In one paragraph

Article in European heart journal supplements : journal of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Short-term deceleration capacity: a novel non-invasive indicator of parasympathetic activity in patients undergoing pulmonary vein isolation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Marco RebecchiDepartment of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome 00100, Italy.
Ermenegildo De RuvoDepartment of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome 00100, Italy.
Marianna Sgueglia
Carlo LavalleDepartment of Cardiovascular, Respiratory, Nephrology, Anaesthesiology and Geriatric Sciences, Sapienza University of Rome, Viale del Policlinico, 155, Rome 00161, Italy.
Stefano CanestrelliDepartment of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome 00100, Italy.
Alessandro PolitanoDepartment of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome 00100, Italy.
Ilaria JacomelliDepartment of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome 00100, Italy.
Paolo GoliaDepartment of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome 00100, Italy.
Cinzia CrescenziDepartment of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome 00100, Italy.
Lucia De LucaDepartment of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome 00100, Italy.
Marco PanuccioDepartment of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome 00100, Italy.
Alessandro FagagniniDepartment of Cardiology, Policlinico Casilino, Via Casilina 1049, Rome 00100, Italy.
Leonardo Calò
Policlinico Casilino · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For several years, the autonomic nervous system has played a central role in the pathophysiological mechanism of atrial fibrillation (AF), so much so that it has been considered one of the cornerstones of Coumel's triangle. The clinical and therapeutic management of AF secondary to sympatho-vagal imbalance represents one of the most important examples of how precision medicine should be applied. Increasing knowledge of this kind of arrhythmias has made it possible to select specific antiarrhythmic drugs and to diversify their use according to vagal or adrenergic AF forms. Ablative strategies, such as cardioneuroablation and non-direct cardiac neuromodulation methods (such as renal denervation and peripheral vagal stimulation), have gradually emerged. In the possibly near future, there will be a development of new acquisitions regarding new pharmacological therapeutic strategies and gene therapy. Finally, finding an AF in patients experiencing syncopal episodes opens a whole chapter regarding interesting, but also complex, diagnostic and therapeutic strategies, ranging from neurally mediated forms to convulsive seizure that could also increase the risk of sudden death.

Indexed as

Atrial fibrillationAutonomic nervous systemGanglionated plexi ablationSyncope

Identifiers

PMID37125283
PMCPMC10132557
OpenAlexW4367046016

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.