Evidence map›Paper›PMID 37127675›Full record

ArticleScientific reports2023

The Mc4r gene is responsible for the development of experimentally induced testicular teratomas.

Syunsuke Seki, Kaoru Ohura, Takehiro Miyazaki, Abdullah An Naser, Shuji Takabayashi, Eisei Tsutsumi, Toshinobu Tokumoto

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Syunsuke Seki *Department of Bioscience, Faculty of Science, Shizuoka University, Shizuoka, 422, Japan.
Kaoru Ohura *Department of Bioscience, Faculty of Science, Shizuoka University, Shizuoka, 422, Japan.
Takehiro MiyazakiIntegrated Bioscience Section, Graduate School of Science and Technology, National University Corporation Shizuoka University, Ohya 836, Suruga-Ku, Shizuoka, 422-8529, Japan.
Abdullah An NaserDepartment of Bioscience, Faculty of Science, Shizuoka University, Shizuoka, 422, Japan.
Shuji TakabayashiLaboratory Animal Facilities & Services, Preeminent Medical Photonics Education & Research Center, Hamamatsu University School of Medicine, 1-20-1, Handayama, Higashi-Ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Eisei TsutsumiBiological Science Course, Department of Science, Graduate School of Integrated Science and Technology, Shizuoka University, 836 Ohya, Suruga-Ku, Shizuoka, 422-8529, Japan.
Toshinobu TokumotoDepartment of Bioscience, Faculty of Science, Shizuoka University, Shizuoka, 422, Japan. tokumoto.toshinobu@shizuoka.ac.jp.
Shizuoka University · JPHamamatsu University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Teratomas in mice, composed of different tissue types, are derived from primordial germ cells in the fetal gonads. Previously, we identified a locus responsible for experimental testicular teratoma (ETT) formation on chromosome 18, referred to as ett1. The strongest candidate sequence in the ett1 locus was found to be a missense mutation in the melanocortin 4 receptor (Mc4r), Mc4r

Indexed as

TeratomaTesticular NeoplasmsAnimalsFemaleHumansMaleMiceReceptor, Melanocortin, Type 4MC4R protein, humanMC4R protein, mouseReceptor, Melanocortin, Type 4

Identifiers

PMID37127675
PMCPMC10151343
OpenAlexW4367598035

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.