Trial reportInternational urogynecology journal2023
From thigh to pelvis: female genital prolapse repair with an autologous semitendinosus tendon transplant : Data of the German multicenter trial.
Trial report in International urogynecology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 9 citations in OpenAlex.
- [Pelvic floor reconstruction-An interdisciplinary overview].Chirurgie (Heidelberg, Germany) · 2026Article
- Autologous Semitendinosus Hamstring Tendon Transplant for Female Urinary Stress Incontinence Treatment (Anat-SUBLIM: Anatomy for Suburethral Ligamentoplasty): A Cadaver Model.International urogynecology journal · 2026Article
- Postoperative Mobility After Partial Semitendinosus Tendon Harvesting in Pelvic Organ Prolapse Surgery: Results of a Prospective Observational Study.International urogynecology journal · 2026Article
- Percutaneous laparoscopic harvest and trans-vaginal implantation of autologous rectus fascia in the treatment of severe anterior vaginal prolapse.BMC surgery · 2026Article
- vNOTES retroperitoneal uterosacropexy using the semitendinosus tendon.Obstetrics & gynecology science · 2026Article
- [Learning from others-semitendinosus tendon autograft for inguinal hernia repair (HoTT-TAPP) : Case series with demonstration of feasibility].Chirurgie (Heidelberg, Germany) · 2025Article
- Robotic-assisted tendon transplantation-approach for pelvic organ prolapse repair: a case report.Journal of medical case reports · 2025Article
- Implementation of Robotic-Assisted Sacrocervicopexy for Apical Organ Prolapse Using the Semitendinosus Tendon-Pilot Study and Analysis of Clinical Outcome.International urogynecology journal · 2025Article
- Sacrocolpopexy: Alternatives to Mesh Grafts.International urogynecology journal · 2025Review
- Fortifying the foundation: assessing the role of uterine ligament integrity in uterine prolapse and beyond.Archives of gynecology and obstetrics · 2024Review
- [Pelvic floor reconstruction-update 2024: prolapse-associated symptoms and their treatment].Urologie (Heidelberg, Germany) · 2024Review
- Modified Oxford technique of colpopexy for the treatment of uterine and vaginal vault prolapse: a retrospective pilot cohort study.Frontiers in surgery · 2023Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisThe use of synthetic mesh for prolapse and incontinence surgery is discussed controversially and in several countries is either no longer used or permissible. Previous approaches with autologous tissue did not show from a patient´s perspective convincing long-term results. As there have been repeatedly significant complications with synthetic mesh, a new approach is urgently needed. During orthopedics and trauma surgeries, tendons from the thigh have been used for decades to replace cruciate ligament. The procedure of tendon removal from the thigh is fast, easy to learn and morbidity is low. In addition, a long-term durability of the transplant ought to be expected. The objective of this investigation was to show our experience with a semitendinosus tendon instead of a mesh for genital prolapse repair.
methodAfter the first successful attempts using such tendons in cervicosacropexy and pectopexy in patients with genital prolapse, we initiated a national multicenter study in 2020. Five German hospitals participated in order to determine the feasibility of cervicosacropexy with tendon tissue instead of mesh.
resultUp until now, we have operated and observed 113 patients for at least 6 months and have seen stable results in terms of fixation of the apical compartment. The expected low morbidity at the donor site was also confirmed through subjective assessment of the patients (Knee and Osteoarthritis Outcome Score). Improvement of quality of life was confirmed after the procedure with the Short Form Health Survey 12, Version 2.0. The results of this multicenter study showed that the desired elevation of the apical compartment with tendon tissue can be achieved with low morbidity and without a synthetic mesh.
conclusionWomen with uterine prolapse can be treated minimally invasively and with very low morbidity by using the semitendinosus tendon. The involvement of multiple (five) medical centers confirms that the technique is easy to learn and be transferred to other clinical centers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.