Evidence map›Paper›PMID 37137308›Full record

ArticleCurrent biology : CB2023

BUB-1-bound PLK-1 directs CDC-20 kinetochore recruitment to ensure timely embryonic mitoses.

Jack Houston, Midori Ohta, J Sebastián Gómez-Cavazos, Amar Deep, Kevin D Corbett, Karen Oegema, Pablo Lara-Gonzalez, Taekyung Kim, Arshad Desai

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jack HoustonBiomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA 92093, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
Midori OhtaDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA.
J Sebastián Gómez-CavazosDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
Amar DeepDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Kevin D CorbettBiomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA 92093, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Karen OegemaBiomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA 92093, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA; Department of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
Pablo Lara-GonzalezDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA.
Taekyung KimLudwig Institute for Cancer Research, La Jolla, CA 92093, USA; Department of Biology Education, Pusan National University, Busan 46241, Republic of Korea. Electronic address: taekim@pusan.ac.kr.
Arshad DesaiBiomedical Sciences Graduate Program, University of California, San Diego, La Jolla, CA 92093, USA; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Ludwig Institute for Cancer Research, La Jolla, CA 92093, USA; Department of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: abdesai@ucsd.edu.
University of California San Diego · USLudwig Cancer Research · USUniversity of California, Irvine · US

Funding

Kinetochore Specification and FunctionR01GM074215 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DESAI, ARSHAD · 2005 to 2025
$8.2M
Analysis of Centrosome DynamicsR01GM074207 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OEGEMA, KAREN F · 2006 to 2025
$6.6M
Molecular mechanisms of nucleic acid recognition and maintenance in meiosis and innate immunityR35GM144121 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Kevin Daniel Corbett · 2022 to 2026
$2.7M
NIGMS NIH HHS R01 GM074207NIGMS NIH HHS R01 GM074215NIGMS NIH HHS R35 GM144121
6 · The paper itself

Abstract

During mitosis, chromosomes assemble kinetochores to dynamically couple with spindle microtubules.

Indexed as

Caenorhabditis elegansKinetochoresAnaphase-Promoting Complex-CyclosomeAnimalsCaenorhabditis elegans ProteinsCdc20 ProteinsCell Cycle ProteinsCenters for Disease Control and Prevention, U.S.MitosisPolo-Like Kinase 1Protein Serine-Threonine KinasesSpindle ApparatusUnited StatesAnaphase-Promoting Complex-Cyclosomebub-1 protein, C elegansCaenorhabditis elegans ProteinsCdc20 ProteinsCell Cycle ProteinsFZY-1 protein, C elegansplk-1 protein, C elegansPolo-Like Kinase 1Protein Serine-Threonine KinasesAPC/CBub1Cdc20cell cyclecentromereembryogenesiskinetochoremitosisPlk1spindle assembly checkpoint

Identifiers

PMID37137308
PMCPMC10270731
OpenAlexW4367671448

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.