ArticleCritical reviews in environmental science and technology2023
Methodological Challenges in Spatial and Contextual Exposome-Health Studies.
Article in Critical reviews in environmental science and technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- A quantitative intersectional approach to measuring change in built environment amenities and the association with mortality in U.S. counties.Social science & medicine (1982) · 2026Article
- A Geographically Sensitive Neighborhood Exposome-Wide Association Study for Breast Cancer Survival.JAMA network open · 2026Article
- The spatial and contextual exposome and subtypes of hypertensive disorders of pregnancy: a double machine learning-based analysis.Exposome · 2026Article
- The impact of the Social Exposome in Cardiovascular Health and Disease.Journal of precision medicine (Amsterdam, Netherlands) · 2025Article
- Harnessing Geospatial Artificial Intelligence (GeoAI) for Environmental Epidemiology: A Narrative Review.Current environmental health reports · 2025Review
- Nanomedicine-Driven Modulation of the Gut-Brain Axis: Innovative Approaches to Managing Chronic Inflammation in Alzheimer's and Parkinson's Disease.International journal of molecular sciences · 2025Review
- A review of geospatial exposure models and approaches for health data integration.Journal of exposure science & environmental epidemiology · 2025Review
- FHIR PIT: a geospatial and spatiotemporal data integration pipeline to support subject-level clinical research.BMC medical informatics and decision making · 2025Article
- Review
- An exploratory analysis of the impact of area-level exposome on geographic disparities in aggressive prostate cancer.Scientific reports · 2024Article
- Heterogeneous associations of multiplexed environmental factors and multidimensional aging metrics.Nature communications · 2024Article
- Lifetime residential data collection protocol for the Adolescent Brain Cognitive Development (ABCD) Study.MethodsX · 2024Article
- Geospatial Science for the Environmental Epidemiology of Cancer in the Exposome Era.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Spatial scale effects on associations between built environment and cognitive function: Multi-Ethnic Study of Atherosclerosis.Health & place · 2024Article
- The Science of Precision Prevention: Research Opportunities and Clinical Applications to Reduce Cardiovascular Health Disparities.JACC. Advances · 2024Article
- The Chilean exposome-based system for ecosystems (CHiESS): a framework for national data integration and analytics platform.Frontiers in public health · 2024Article
- Enriching Real-world Data with Social Determinants of Health for Health Outcomes and Health Equity: Successes, Challenges, and Opportunities.Yearbook of medical informatics · 2023Article
- Mental Health in Urban Environments: Uncovering the Black Box of Person-Place Interactions Requires Interdisciplinary Approaches.JMIR mHealth and uHealth · 2023Article
- A spatial and contextual exposome-wide association study and polyexposomic score of COVID-19 hospitalization.Exposome · 2023Article
- Climate change, human health, and the exposome: Utilizing OMIC technologies to navigate an era of uncertainty.Frontiers in public health · 2022Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
The concept of the exposome encompasses the totality of exposures from a variety of external and internal sources across an individual's life course. The wealth of existing spatial and contextual data makes it appealing to characterize individuals' external exposome to advance our understanding of environmental determinants of health. However, the spatial and contextual exposome is very different from other exposome factors measured at the individual-level as spatial and contextual exposome data are more heterogenous with unique correlation structures and various spatiotemporal scales. These distinctive characteristics lead to multiple unique methodological challenges across different stages of a study. This article provides a review of the existing resources, methods, and tools in the new and developing field for spatial and contextual exposome-health studies focusing on four areas: (1) data engineering, (2) spatiotemporal data linkage, (3) statistical methods for exposome-health association studies, and (4) machine- and deep-learning methods to use spatial and contextual exposome data for disease prediction. A critical analysis of the methodological challenges involved in each of these areas is performed to identify knowledge gaps and address future research needs.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.