ArticleFrontiers in neuroscience2023
Hemispheric lateralization of white matter microstructure in children and its potential role in sensory processing dysfunction.
Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Lifespan Trajectories of Asymmetry in White Matter Tracts.Human brain mapping · 2026Article
- Soccer heading and white matter microstructural changes: a two-year longitudinal cohort study.Brain imaging and behavior · 2026Article
- Lifespan Trajectories of Asymmetry in White Matter Tracts.bioRxiv : the preprint server for biology · 2025Article
- White matter microstructure of children with sensory over-responsivity is associated with affective behavior.Journal of neurodevelopmental disorders · 2024Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Diffusion tensor imaging (DTI) studies have demonstrated white matter microstructural differences between the left and right hemispheres of the brain. However, the basis of these hemispheric asymmetries is not yet understood in terms of the biophysical properties of white matter microstructure, especially in children. There are reports of altered hemispheric white matter lateralization in ASD; however, this has not been studied in other related neurodevelopmental disorders such as sensory processing disorder (SPD). Firstly, we postulate that biophysical compartment modeling of diffusion MRI (dMRI), such as Neurite Orientation Dispersion and Density Imaging (NODDI), can elucidate the hemispheric microstructural asymmetries observed from DTI in children with neurodevelopmental concerns. Secondly, we hypothesize that sensory over-responsivity (SOR), a common type of SPD, will show altered hemispheric lateralization relative to children without SOR. Eighty-seven children (29 females, 58 males), ages 8-12 years, presenting at a community-based neurodevelopmental clinic were enrolled, 48 with SOR and 39 without. Participants were evaluated using the Sensory Processing 3 Dimensions (SP3D). Whole brain 3 T multi-shell multiband dMRI (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.