A CDK-Dependent Phosphorylation of a Novel Domain of Rif1 Regulates its Function during Telomere Damage and Other Types of Stress.

Cameron M Robertson, Yuan Xue, Shobir Chowdhury, Laura Maringele

Open access · hybridAbstract read

In one paragraph

Article in Molecular and cellular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.2field-weighted citation impact, top 43% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cameron M RobertsonNewcastle University Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.

Yuan XueNewcastle University Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.

Shobir ChowdhuryNewcastle University Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.

Laura MaringeleNewcastle University Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0002-0056-1022

Newcastle University · GB

Funding

Biotechnology and Biological Sciences Research Council

6 · The paper itself

Abstract

Rif1 mediates telomere length, DNA replication, and DNA damage responses in budding yeast. Previous work identified several posttranslational modifications of Rif1, however none of these was shown to mediate the molecular or cellular responses to DNA damage, including telomere damage. We searched for such modifications using immunoblotting methods and the

Indexed as

Repressor ProteinsSaccharomyces cerevisiae ProteinsTelomereTelomere-Binding ProteinsDNA ReplicationPhosphorylationSaccharomyces cerevisiaeCdc13 protein, S cerevisiaeRepressor ProteinsRIF1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTelomere-Binding Proteinsbudding yeastcyclin-dependent kinasesDNA damage checkpointsRif1telomere

Identifiers

PMID37140180

DOI10.1080/10985549.2023.2193768

PMCPMC10184589

OpenAlexW4368358597

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.