Evidence mapPaperPMID 37143039Full record

ArticleJournal of nanobiotechnology2023

Cooperative phototherapy based on bimodal imaging guidance for the treatment of uveal melanoma.

Tong Huang, Xinzhi Xu, Chen Cheng, Jianxin Wang, Liping Yang

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Chlorin Activity Enhancers for Photodynamic Therapy.Molecules (Basel, Switzerland) · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Tong HuangChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, P. R. China.
Xinzhi XuDepartment of Ultrasound, Chongqing University Cancer Hospital, Chongqing, 400030, P. R. China.
Chen ChengChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, P. R. China.
Jianxin WangChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, P. R. China. wjxhmu@163.com.
Liping YangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, P. R. China. 306843@hospital.cqmu.edu.cn.
Dalian Medical University · CNChongqing Cancer Hospital · CNChongqing Medical University · CNFirst Affiliated Hospital of Harbin Medical University · CN

Funding

China Postdoctoral Science Foundation 2022MD723746
6 · The paper itself

Abstract

backgroundUveal melanoma (UM) is adults' most common primary intraocular malignant tumor, prone to metastasis and high mortality. Eyeball enucleation commonly used in the clinic will lead to permanent blindness and mental disorders. Thus, new methods are urgently needed to diagnose and treat UM early to preserve patients' vision. METHODS AND

resultsHerein, multifunctional nanoparticles (NPs) were synthesized by loading chlorin e6 (Ce6) in poly-lactic-co-glycolic acid (PLGA) NPs and wrapping Fe

conclusionThis noninvasive NIR light-triggered cooperative phototherapy can easily penetrate eye tissue and overcome the disadvantage of limited penetration of phototherapy. Therefore, cooperative phototherapy is expected to be used in fundus tumors. This treatment model is applied to UM for the first time, providing a promising strategy and new idea for integrating the diagnosis and treatment of UM.

Indexed as

MelanomaNanoparticlesPhotochemotherapyPorphyrinsCell Line, TumorFerric CompoundsHumansPhototherapyUveal MelanomaUveal NeoplasmsFerric CompoundsPorphyrinsDual-modal imagingNanomedicinePhotodynamic therapyPhotothermal therapyUveal melanoma

Identifiers

PMID37143039
PMCPMC10161622
OpenAlexW4372335888

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.