Evidence map›Paper›PMID 37145378›Full record

ArticleMolecular neurobiology2023

Evaluation of Potential Neuroprotective Effects of Vanillin Against MPP

Linchi Rani, Balaram Ghosh, Mir Hilal Ahmad, Amal Chandra Mondal

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Turkish journal of medical sciences · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Neuroprotection of Andrographolide against Neurotoxin MPPInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Linchi RaniLaboratory of Cellular and Molecular Neurobiology, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India, 110067.
Balaram GhoshMidnapore Medical College and Hospital, West Medinipur, Kolkata, West Bengal, India.
Mir Hilal AhmadLaboratory of Cellular and Molecular Neurobiology, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India, 110067.
Amal Chandra MondalLaboratory of Cellular and Molecular Neurobiology, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India, 110067. acmondal@mail.jnu.ac.in.ORCID http://orcid.org/0000-0003-0491-7804
Jawaharlal Nehru University · INMidnapore Medical College and Hospital · IN

Funding

Indian Council of Medical Research 45/07/2019/MP/BMS
6 · The paper itself

Abstract

Parkinson's disease (PD) is a progressive neurodegenerative condition. The pathogenesis of PD is still unknown, and drugs available for PD treatment either have side effects or have suboptimal efficacy. Flavonoids are potent antioxidants having little toxicity with extended use, suggesting they might hold promising therapeutic potential against PD. Vanillin (Van) is a phenolic compound that has exhibited neuroprotective properties in various neurological disorders, including PD. However, the neuroprotective role of Van in PD and its underlying mechanisms are scarce and therefore need more exploration. Here, we evaluated the neuroprotective potential of Van and its associated mechanisms against MPP

Indexed as

NeuroblastomaNeuroprotective AgentsParkinson DiseaseAnimalsApoptosisBenzaldehydesCell Line, TumorDopaminergic NeuronsGlycogen Synthase Kinase 3 betaHumansMiceMice, Inbred C57BLBenzaldehydesGlycogen Synthase Kinase 3 betaNeuroprotective AgentsvanillinApoptosisMPP+/MPTPOxidative stressParkinson’s diseaseTyrosine hydroxylaseVanillin

Identifiers

PMID37145378
OpenAlexW4372294854

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.