Evidence map›Paper›PMID 37150604›Full record

SynthesisEnvironmental health and preventive medicine2023

Alcohol consumption and the risk of heart failure: the Suita Study and meta-analysis of prospective cohort studies.

Ahmed Arafa, Rena Kashima, Yoshihiro Kokubo, Masayuki Teramoto, Yukie Sakai, Saya Nosaka, Haruna Kawachi, Keiko Shimamoto, Chisa Matsumoto, Qi Gao and 1 more

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Environmental health and preventive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ahmed ArafaDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.ORCID http://orcid.org/0000-0002-3335-2243
Rena KashimaDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.
Yoshihiro KokuboDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.
Masayuki TeramotoDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.
Yukie SakaiDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.
Saya NosakaDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.
Haruna KawachiDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.
Keiko ShimamotoDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.
Chisa MatsumotoDepartment of Cardiology, Center for Health Surveillance and Preventive Medicine, Tokyo Medical University Hospital.
Qi GaoDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center.
Chisato IzumiDepartment of Heart Failure and Transplantation, National Cerebral and Cardiovascular Center.
National Cerebral and Cardiovascular Center · JPBeni-Suef University · EGTokyo Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol consumption is a modifiable lifestyle, but its role in heart failure (HF) development is controversial. Herein, we investigated the prospective association between alcohol consumption and HF risk.

methodsA total of 2,712 participants (1,149 men and 1,563 women) from the Suita Study were followed up every two years. Cox regression was applied to calculate the hazard ratios (HRs) and 95% confidence intervals (95% CIs) of HF risk for heavy drinking (≥46 g/day in men or ≥23 g/day in women) and never drinking compared to light drinking (<23 g/day in men or <11.5 g/day in women). Then, we combined the results of the Suita Study with those from other eligible prospective cohort studies in a meta-analysis using the random-effects model.

resultsIn the Suita Study, within a median follow-up period of 8 years, 319 HF cases (162 in men and 157 in women) were detected. In men, but not women, never and heavy drinking carried a higher risk of HF than light drinking: HRs (95% CIs) = 1.65 (1.00, 2.73) and 2.14 (1.26, 3.66), respectively. Alike, the meta-analysis showed a higher risk of HF among heavy drinkers: HR (95% CI) = 1.37 (1.15, 1.62) and abstainers: HR (95% CI) = 1.18 (1.02, 1.37).

conclusionWe indicated a J-shaped association between alcohol consumption and HF risk among Japanese men. The results of the meta-analysis came in line with the Suita Study. Heavy-drinking men should be targeted for lifestyle modification interventions.

Indexed as

Alcohol DrinkingHeart FailureHumansMaleProportional Hazards ModelsProspective StudiesRisk FactorsAlcohol consumptionHeart failureJapanMeta-analysisProspective cohort

Identifiers

PMID37150604
PMCPMC10188284
OpenAlexW4367728256

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.