Evidence map›Paper›PMID 37153903›Full record

ArticleExperimental and therapeutic medicine2023

Acrylamide induces human chondrocyte cell death by initiating autophagy‑dependent ferroptosis.

Hui Wang, Zizheng Tang, Shasha Liu, Kangqi Xie, Hua Zhang

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hui WangDepartment of Rheumatology, The Fourth Hospital of Jinan, Jinan, Shandong 250031, P.R. China.
Zizheng TangDepartment of Rheumatology, The Fourth Hospital of Jinan, Jinan, Shandong 250031, P.R. China.
Shasha LiuDepartment of Rheumatology, The Fourth Hospital of Jinan, Jinan, Shandong 250031, P.R. China.
Kangqi XieDepartment of Rheumatology, The Fourth Hospital of Jinan, Jinan, Shandong 250031, P.R. China.
Hua ZhangDepartment of Rheumatology, Zaozhuang Municipal Hospital (Affiliated Hospital of Jining Medical College), Zaozhuang, Shandong 277102, P.R. China.
Fourth People’s Hospital of Jinan · CNZaozhuang Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acrylamide (ACR) is formed during heat treatment of foodstuffs and ACR may serve as a probable malignant neoplastic disease agent in all organs and tissues of the human body. However, it is unknown if ACR is associated with ankylosing spondylitis (AS) pathogenesis. Cell viability and proliferation were determined using CCK-8 assay and EdU staining. Flow cytometry was used to determine cell death and cell cycle arrest. Intracellular lipid reactive oxygen species, Fe

Indexed as

acrylamideAMPK/ULK1/mTOR signalingankylosing spondylitisautophagyferroptosis

Identifiers

PMID37153903
PMCPMC10160918
OpenAlexW4365145011

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.