Evidence map›Paper›PMID 37158798›Full record

ArticleThe Journal of sports medicine and physical fitness2023

Excess adiposity contributes to higher ambulatory central blood pressure and arterial stiffness in physically inactive young adults.

Michael S Brian, Amanda R Blier, Braeden M Alward, Emily E Waite, Maison P D'Amelio, Marialena A Shaw, Daniel F O'Neill, Sushela S Chaidarun

Open access · greenAbstract read
In one paragraph

Article in The Journal of sports medicine and physical fitness, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Michael S BrianDepartment Health and Human Performance, Plymouth State University, Plymouth, NH, USA - michael.brian@unh.edu.
Amanda R BlierDepartment Health and Human Performance, Plymouth State University, Plymouth, NH, USA.
Braeden M AlwardDepartment Health and Human Performance, Plymouth State University, Plymouth, NH, USA.
Emily E WaiteDepartment of Kinesiology, University of New Hampshire, Durham, NH, USA.
Maison P D'AmelioDepartment of Kinesiology, University of New Hampshire, Durham, NH, USA.
Marialena A ShawDepartment Health and Human Performance, Plymouth State University, Plymouth, NH, USA.
Daniel F O'NeillThe Alpine Clinic, Plymouth, NH, USA.
Sushela S ChaidarunEndocrine Section, Department of Medicine, Dartmouth Hitchcock Medical Center, Dartmouth, NH, USA.
Plymouth State University · USUniversity of New Hampshire · USDartmouth–Hitchcock Medical Center · USPlymouth Hospital · GB

Funding

Ultrastructural analysis of axonal Kv2-mediated endoplasmic reticulum/plasma membrane (ER/PM) junctionsP20GM103506 · NIGMS · DARTMOUTH COLLEGE · PI WILLIAM R GREEN · 2012 to 2026
$60.1M
NIGMS NIH HHS P20 GM103506
6 · The paper itself

Abstract

backgroundIt remains unknown if physical inactivity and excess adiposity increases 24-h central blood pressure and arterial stiffness in young adults. This study examined 24-h central blood pressure and indirect measures of arterial stiffness (e.g., central pulse pressure) in physically inactive young adults with and without excess adiposity.

methodsBody fat and ambulatory 24-h blood pressure were measured in 31 young adults (men: 22±4 years, N.=15; women: 22±5 years, N=16). Multi-frequency bioelectrical impedance measured body fat. Normal adiposity was defined as <20% body fat in men and <32% body fat in women, whereas excess adiposity was defined as ≥20% and ≥32% in men and women, respectively. Ambulatory 24-h central blood pressure was calculated based on brachial blood pressure and volumetric displacement waveforms.

resultsBy design, the normal adiposity group had a lower body fat percentage (men: 15.5±4.6%; women: 20.8±2.5%) compared to the physically inactive excess adiposity group (men: 29.8±5.4%; women: 34.3±7.5%). Men and women with excess adiposity group had elevated central blood pressure (central systolic, P<0.05 vs. normal adiposity groups). Central pulse pressure was elevated in the excess adiposity group (men: 45±5 mmHg; women: 41±9 mmHg) compared to normal adiposity groups (men: 36±4 mmHg; women: 32±3 mmHg, P<0.05 for both), while other arterial stiffness (augmentation index and ambulatory arterial stiffness index) measures trended toward significance only in men with excess adiposity.

conclusionsPhysically inactive men and women with excess adiposity have increased 24h central blood pressure and pulse pressure compared to physically inactive young adults with normal adiposity.

Indexed as

HypertensionVascular StiffnessAdiposityBlood PressureFemaleHumansMaleObesitySedentary BehaviorYoung Adult

Identifiers

PMID37158798
PMCPMC11382482
OpenAlexW4375948638

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.