Evidence map›Paper›PMID 37160355›Full record

ArticleRNA (New York, N.Y.)2023

A temporal difference in the stabilization of two mRNAs with a 3' iron-responsive element during iron deficiency.

Gregory J Connell, Ikedinachukwu Michael Abasiri, Elizabeth H Chaney

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gregory J ConnellDepartment of Pharmacology, Medical School, University of Minnesota, Minneapolis, Minnesota 55455, USA conne018@umn.edu.
Ikedinachukwu Michael Abasiri *Department of Pharmacology, Medical School, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Elizabeth H Chaney *Department of Pharmacology, Medical School, University of Minnesota, Minneapolis, Minnesota 55455, USA.
University of Minnesota Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interactions of iron regulatory proteins (IRPs) with mRNAs containing an iron-responsive element (IRE) maintain cellular iron homeostasis and coordinate it with metabolism and possibly cellular behavior. The mRNA encoding transferrin receptor-1 (

Indexed as

IronIron Deficiencies3' Untranslated RegionsHEK293 CellsHumansReceptors, TransferrinRNA, Messenger3' Untranslated RegionsIronReceptors, TransferrinRNA, MessengerCDC14Airon-responsive elementsmRNA stabilityRoquintransferrin receptor-1

Identifiers

PMID37160355
PMCPMC10351883
OpenAlexW4376117252

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.