Evidence map›Paper›PMID 37162092›Full record

ReviewJournal of diabetes science and technology2024

Challenges of Glycemic Control in People With Diabetes and Advanced Kidney Disease and the Potential of Automated Insulin Delivery.

Jean C Lu, Petrova Lee, Francesco Ierino, Richard J MacIsaac, Elif Ekinci, David O'Neal

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Journal of diabetes science and technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06463483 narecruitingnot on this mapstarted 2025, after this paper: background citation

Glucose Control With Medtronic 780G System in Adults With Diabetes and Advanced Renal Disease

TypeinterventionalSponsorImperial College LondonRan2025 to 2027Enrolled12ConditionsChronic Kidney Diseases, Diabetes MellitusArmsMedtronic 780G System, Continuous Glucose Monitoring
NCT07422532 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

An Open-label, Multi-centre, Randomised Controlled Trial to Assess the Efficacy, Safety and Utility of Automated Insulin Delivery in People With Type 2 Diabetes and Sub-optimal Glycaemia Undergoing Haemodialysis

TypeinterventionalSponsorImperial College LondonRan2026 to 2027Enrolled84ConditionsType 2 Diabetes, Chronic Kidney Disease 5DArmsOmnipod 5, Insulin injections
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jean C LuDepartment of Medicine, St Vincent's Hospital Melbourne, The University of Melbourne, Fitzroy, VIC, Australia.ORCID 0000-0002-3151-232X
Petrova LeeDepartment of Nephrology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia.
Francesco IerinoDepartment of Medicine, St Vincent's Hospital Melbourne, The University of Melbourne, Fitzroy, VIC, Australia.
Richard J MacIsaacDepartment of Medicine, St Vincent's Hospital Melbourne, The University of Melbourne, Fitzroy, VIC, Australia.
Elif EkinciAustralian Centre for Accelerating Diabetes Innovations, The University of Melbourne, Parkville, VIC, Australia.
David O'NealDepartment of Medicine, St Vincent's Hospital Melbourne, The University of Melbourne, Fitzroy, VIC, Australia.ORCID 0000-0002-0870-4032
The University of Melbourne · AUSt Vincent's Hospital Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes is the leading cause of chronic kidney disease (CKD) and end-stage kidney disease in the world. It is known that maintaining optimal glycemic control can slow the progression of CKD. However, the failing kidney impacts glucose and insulin metabolism and contributes to increased glucose variability. Conventional methods of insulin delivery are not well equipped to adapt to this increased glycemic lability. Automated insulin delivery (AID) has been established as an effective treatment in patients with type 1 diabetes mellitus, and there is emerging evidence for their use in type 2 diabetes mellitus. However, few studies have examined their role in diabetes with concurrent advanced CKD. We discuss the potential benefits and challenges of AID use in patients with diabetes and advanced CKD, including those on dialysis.

Indexed as

Glycemic ControlHypoglycemic AgentsInsulinInsulin Infusion SystemsBlood GlucoseDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NephropathiesHumansRenal Insufficiency, ChronicBlood GlucoseHypoglycemic AgentsInsulinartificial pancreasautomated insulin deliverychronic kidney diseasediabetesdialysisinsulin pump

Identifiers

PMID37162092
PMCPMC11531035
OpenAlexW4376106532

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.